宋利萍老师，1992-2000年就读于辽宁大学医学院， (原锦州医学院) 获得学士及硕士学位。2000-2003年获得中科院遗传所人类基因组博士学位，2003-2007前往美国在洛杉矶儿童医院进行博士后的培训，2007-2009 任资深博士后。2009-2010贝勒医学院/德州儿童医院任 Instructor。2010 至今，在美国The University of Texas at Houston/Texas大学进行病理住院医师培训。现在为PGY3 病理住院医。宋老师的临床和研究兴趣包括血液肿瘤病理、肿瘤免疫微环境以及iNKT介导的肿瘤免疫治疗。

Peer-reviewed publications:

Daofeng Liu ,Liping Song ,Jie Wei ,Amy Courtney ,Xiuhua ,Ekaterina Marinova, Linjie Guo, ,Andras Heczey, Shahab Asgharzadeh ,Eugene Kim ,Gianpietro Dotti ,Leonid Metelitsa  IL-15 protects NKTs from inhibition by tumor-associated macrophages and enhances anti-metastatic activity. J Clin Invest. 2012 Jun. 122(6):2221-2233

Xiong G, Husseiny MI, Song L, Erdreich-Epstein A, Shackleford GM, Seeger RC, J?ckel D, Hensel M, Metelitsa LS. Novel cancer vaccine based on genes of Salmonella pathogenicity island 2. Int J Cancer. 2010 Jun 1; 126(11):2622-34.

Liping Song, Shahab Asgharzadeh, Jill Salo, Kelly Engell, Hong-wei Wu, Richard Sposto, Tasnim Ara, Ayaka M. Silverman, Yves A. DeClerck, Robert C. Seeger, and Leonid S. Metelitsa. Valfa24-invariant Natural Killer T Cells Mediate Anti-tumor Activity via Killing of Tumor-Associated Macrophages J Clin Invest. 2009 Jun; 119(6):1524-36.

Ara T, Song L, Shimada H, Keshelava N, Russell HV, Metelitsa LS, Groshen SG, Seeger RC, DeClerck YA.Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells. Cancer Res. 2009 Jan 1;69(1):329-37.

Song L, Ara T, Wu HW, Woo CW, Reynolds CP, Seeger RC, DeClerck YA, Thiele CJ, Sposto R, Metelitsa LS. Oncogene MYCN regulates localization of NKT cells to the site of disease in neuroblastoma. J Clin Invest. 2007 Sep; 117(9): 2702-12

Xuequan Lu, Liping Song*, Leonid S. Metelitsa, and Robert Bittman Synthesis and Immunostimulatory Properties of alfa-C-Galactosylceramide Analogues with a 1-Methylene Tether to D-ribo-Phytosphingosine and with a 2-Methylene Tether to D-arabino-Phytosphingosine. ChemBioChem 2006 Nov;7(11):1750-6. (*co-first author)

Baev DV, Peng X, Song L, Barnhart JR, Crooks GM, Weinberg KI, Metelitsa LS. Distinct Homeostatic Requirements of CD4+ and CD4- Subsets of Vα24-invariant Natural Killer T cells in Humans. Blood. 2004 Dec; 104(13): 4150-4156.

Liu J, Zhao Q, Zhao B, Cheng J, Wang X, Song L, Zhong Z, Lin Q, Huang H. A new format of single chain tri-specific antibody with diminished molecular size efficiently induces ovarian tumor cell killing. Biotechnol Lett. 2005 Nov; 27(22): 1821-

…Weidong Bao, ……Liping Song…Genfeng Zhu Finishing Group, International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome, Nature 431, 931-945 (2004) Supplementary Information for "Finishing the euchromatic sequence of the human genome, Full Author List, 13-Beijing Genomics Institute

Zhang Z, Song LP, Fang M, Wang F, He D, Zhao R, Liu J, Zhou ZY, Yin CC, Lin Q, Huang HL. Production of soluble and functional engineered antibodies in Escherichia coli improved by FkpA. Biotechniques. 2003 Nov; 35(5): 1032-8, 1041-2

Liping Song, Julong Cheng, Xiangbin Wang, Zhong Zhang et al., A new model of recombinant single-chain trispecific antibody resulting the cytotoxicity directed against tumor cells. Acta Biochimica et Biophysica Sinica, 2003, 6:503-510

Song L.P., Huang H.L. Protein splicing and its application. Sheng Wu Gong Cheng Xue Bao. 2003 Mar; 19(2): 249-54.

…Jingyue Bao, ……Liping Song…Zhen Zhu Initial Sequencing and analysis of the Human Genome, Nature 409, 860 - 921 (2001) Supplementary Information for "Initial Sequencing and Analysis of the Human Genome, Full Author List, Beijing Genomics Institute/Human Genome Center, Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China

Abstract publication:

Liping Song, Xiaolin Wu, Jennifer Reopke, Plasmablastic Lymphoma of the Ascending colon: A Case Report. CAP 2011  Annual Meeting, Dallas, TX.

Liping Song, Daofeng Liu, Leonid Metelitsa, Primary medulloblastomas express functional CD1d and can be targeted for immunotherapy with NKT cells. CAP 2011 Annual Meeting, Dallas, TX.（ second place award）

Liping Song, Daofeng Liu, Leonid Metelitsa Tumor-associated macrophages suffocate NKT cells: a novel tumor escape mechanism and a target for therapy CAP 2011 Annual Meeting, Dallas, TX.

Liping Song, Tatiana V. Yakoushina Signet Ring Cell Variant of Follicular Lymphoma and a Diagnostic Dilemma: A Case Report CAP 2012 Annual Meeting, San Diego, California, September 9 - 12, 2012.

Liping Song, Tatiana V. Yakoushina Microscopic Sertoli Cell Nodule in Fallopian Tube: First Case Report. CAP 2012 Annual Meeting, San Diego, California, September 9 - 12, 2012.

Liping Song, Leonid Metelitsa. (2004, November). MYCN regulates CCL2/MCP-1 expression and localization of Va24-invariant Natural Killer T cells in neuroblastoma: a mechanism of immune escape and a target for immunotherapy. International Society for Biological Therapy of Cancer 19th Annual Meeting; San Francisco, CA.

Liping Song, Tasnim Ara, Hong-Wei Wu, Patrick C. Reynolds, Robert C. Seeger, Yves A. DeClerck, and Leonid S. Metelitsa.. (2006, May). MYCN Oncogene Regulates CCL2 Expression and Localization of Natural Killer T Cells in Neuroblastoma. Advances in Neuroblastoma Research; Los Angeles, CA.