Curriculum Vitae
PERSONAL INFORMATION
Name: Wenqing Cao
601 Elmwood Ave, G5253, Rochester, NY 14642
Telephone-Work: 585-275-7562
Fax Number: 585-273-3637
E-mail: wenqing_cao@URMC.Rochester.edu
EDUCATION
1992-1995 M.S. in Medical Science, Excellent
Union Hospital, Tongji Medical University, Wuhan, China
1987-1992 M.D., Honors
Union Hospital, Tongji Medical University, Wuhan, China
POSTDOCTORAL (OR RESIDENCY) TRAINING
2005-2009 Residency in Anatomic and Clinical Pathology, Department of Pathology
Northwestern University Feinberg School of Medicine/McGaw Medical Center
Chicago, IL
1996-1997 Residency in Dermatology
Union Hospital, Tongji Medical University, Wuhan, China
1995-1996 Residency in Internal Medicine
Union Hospital, Tongji Medical University, Wuhan, China
FELLOWSHIP AWARDS
2009-2010 Fellowship in Gastrointestinal/liver Pathology, Department of Pathology
Mount Sinai School of Medicine, New York, NY
FACULTY APPOINTMENTS
2010-present Assistant Professor, Department of Pathology and Laboratory Medicine,
University of Rochester Medical Center, Rochester, NY
PROFESSIONAL HOSPITAL AND ADMINISTRATIVE APPOINTMENTS
2010-present Attending Pathologist, Department of Pathology and Laboratory Medicine, Strong Memorial Hospital (SMH) and Highland Hospital (HH), Rochester, NY
2010-present Attending Pathologist, Department of Pathology and Laboratory Medicine, Highland
Hospital (HH), Rochester, NY
MEMBERSHIPS IN NATIONAL AND INTERNATIONAL ACADEMIC PROFESSIONAL
ORGANIZATIONS
2012-present American Gastroenterological Association (AGA)
2012-present Hans Popper Hepatopathology Society (HPHS)
2010-present Rodger C. Haggitt Gastrointestinal Pathology Society (GIPS)
2005-present United States and Canadian Academy of Pathology (USCAP)
2005-present American Society for Clinical Pathology (ASCP)
2005-present College of American Pathologists (CAP)
2005-present Chinese American Pathology Association (CAPA)
HONORS AND AWARDS
2008 Resident research award ($3000), Northwestern University McGaw Medical Center
2007 Resident Research Symposium Top Ten, American Society of Clinical Pathology
ASCP Annual meeting, New Orleans
2007 Goldberg Family Charitable Trust Travel Award, Northwestern Memorial Foundation
2006 Goldberg Family Charitable Trust Travel Award, Northwestern Memorial Foundation
1988-1991 University Scholarship, Tongji Medical University
SCIENTIFIC REVIEW ACTIVITY
2013- Editory board member, Journal of Clinical Hepatology
2012- Reviewer, Diagnostic Pathology
2012- Reviewer, Disease of Esophagus
2011- Reviewer, MedEdPORTAL
RESEARCH ACTIVITIES
2010-present Assistant Professor, Department of Pathology and Laboratory Medicine, URMC
Correlation of MicroRNA and mRNA expression profile in fatty liver disease
Evaluation of Noise Reduction Acoustic Radiation Force Elastograph in rat liver fibrosis model.
The roles of inflammation including M2 macrophages, microenvironment in initiation, progression and metastasis of esophageal adenocarcinoma
Metastasis associated colon cancer 1 (MACC1), a potential indicator for more aggressive treatment for selective patients with early stage colorectal cancer.
Ampullary and bile duct biopsies: diagnostic value of HMGAs, P53 and beta-catenin
Effect of direct or developmental exposure to Bisphenol A on the severity of
experimental inflammatory colitis in mice
2009-2010 Fellow, Department of Pathology, the Mount Sinai Medical Center, New York City, NY
Correlation between ATG16L1 and NOD2 Gene Crohn's Disease-Associated Risk Alleles with Abnormal Ileal Paneth Cell Morphology
2005-2009 Resident, Department of Pathology, Northwestern Memorial Hospital, McGaw Medical Center, Chicago, IL
Inhibitory effect of Celecoxib, Nonsteroidal Anti-inflammatory Drug, on Spontaneously Developed Hepatocellular Carcinomas in AOX Null Mice
Clinical and pathologic study on pancreatic cystic lesions
Diagnostic and prognostic biomarkers in human GI malignancies
Flow cytometry study on multiple myeloma
2003-2005 Research Associate, Department of Medicine, Evanston Northwestern Healthcare, Evanston, IL
Effect of ApoE on glia-mediated inflammation induced by oligomeric versus fibrillar amyloid beta 1-42.
1998-2003 Research Associate, Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL
Mice and rat models of peroxisome proliferator-induced hepatocarcinogenesis; acyl-CoA oxidase deficient mice model of spontaneous hepatocarcinogenesis
PRESENTATIONS AT MAJOR NATIONAL OR INTERNATIONAL PROFESSIONAL MEETINGS
1. Zakharov V, Ren B, Ryan C and Cao W. Diagnostic value of HMGAs, p53 and β-catenin in discriminating adenocarcinoma from adenoma or reactive atypia in ampulla and common bile duct biopsies. USCAP, Baltimore, Mar 2013. Platform Presentation.
2. Barry CT, McCall MN, Almudevar A, Cao W, Mooney R. Correlation of miRNA and mRNA expression profiles in fatty liver disease. The American Association for the Study of Liver Diseases (AASLD) 63rd annual meeting. Boston, Nov 2012. Poster presentation.
3. Ren B, Zakharov V, Ryan C, McMahon L, Yang Q, and Cao W. Diagnostic and Prognostic Significance of MACC1 and MET in Rectal Adenoma and Adenocarcinoma from Transanal Endoscopic Microsurgery. CAP, San Diageo, Sep 2012. Poster presentation.
4. Barry CT, Hah Z, Partin A, Cao W, Mooney R, Rubens D and Parker K. Ultrasonographic Steatography is Sensitive in Detecting Low Levels of Hepatic Steatosis. American Transplant Congress, Boston, June 2012. Poster presentation.
5. Ren B, Zakharov V, Ryan C, McMahon L, Qi Y, and Cao W. MACC1, a Potential Diagnostic Marker for Early Stage Colorectal Cancer. 101st USCAP meeting, Vancouver, Canada, March 2012. Poster presentation.
6. Cao W, Boedecker EC, Frank DN, Cadwell K, Mayer L, Stappenbeck TS, Sartor RB, Li E, Harpaz N. Correlation between ATG16L1 and NOD2 Gene Crohn's Disease-Associated Risk Alleles with Abnormal Ileal Paneth Cell Morphology. 99th USCAP meeting, Washington DC, 2010. Poster presentation.
7. Cao W, Liao J, Rao MS and Yang GY. Ampullary biopsies: Morphological features and useful biomarker panel of adenocarcinoma and adenoma- A single institutional experience on 273 ampullary biopsies. 98th USCAP meeting, Boston, 2009. Poster presentation.
8. Cao W, Adley BP, Zhang M, Liao J, Talamonti M, Bentrem D, Rao MS and Yang GY. Mucinous Nonneoplastic Cyst of the Pancreas: Apomucin Profile Distinct this Entity from Intraductal Papillary Mucinous Neoplasm. 97th USCAP meeting, Denver, 2008. Poster presentation.
9. Cao W, Zhang M, Liao J, Rao SM and Yang GY. Acinal-ductal Mucinous Metaplasia in Pancreas: Pathogenesis and Immunophenotype. ASCP annual meeting, New Orleans, 2007. Oral presentation.
10. Cao WQ, Sumugod R, Lindholm P and Ramsy G. Same partial weak D phenotypes in a Caucasian mother and her baby girl- a case study. Illinois Association of Blood Banks Case Studies, February 2007. Oral presentation.
11. Cao WQ, Wiseman W, Kashireddy P and Rao MS. Inhibiotry effect of Celecoxib, Nonsteroidal Anti-inflammatory Drug, on Spontaneously Developed Hepatocellular Carcinomas in AOX Null Mice. 95th USCAP Pathology, San Diego, 2007. Poster presentation.
12. Cao WQ, Nelson BP, Goolsby CL, Singhal S and Peterson LC. Lack of Stability of Immunophenotype in Plasma Cell Myeloma. 95th USCAP Pathology, San Diego, 2007. Poster presentation.
13. Cao WQ and Laskin W. Malignant glomus tumor. Presented at the Illinois Registry of Anatomic Pathology (IRAP) Meeting, 2006. Oral presentation.
14. Cao WQ, Talamonti M and Rao MS. Calreticulin Expression in Ductal Adenocarcinoma and Islet Tumor of the Pancreas. International Academy of Pathology (IAP), 100th annual meeting, Montreal, Canada, 2006. Poster presentation.
15. Cao WQ and Rao MS. Histological Pattern and Hormone Receptor Status in Breast Carcinoma in Women Over the age of 70 years. International Academy of Pathology (IAP), 100th annual meeting, Montreal, Canada, 2006. Poster presentation.
16. Cao WQ, Kashireddy P and Rao MS. Expression of Nuclear Receptor Co-activator PRIP (Peroxisome Proliferator-Activated Receptor Interacting Protein) in Human Hepatocellular Carcinomas. 95th USCAP meeting, Atlanta, 2006. Poster presentation.
17. Cao WQ, Manelli AM and LaDu MJ. Effect of ApoE on glia-mediated inflammation induced by oligomeric versus fibrillar Amyloid beta 1-42. Society for Neuroscience, 34th annual meeting, 2004. Poster presentation.
18. Kashireddy P, Cao WQ and Rao MS. Ciprofibrate-induced cell proliferation but not peroxisome proliferation is affected by choline deficient diet. 91st USCAP meeting, Chicago, 2002. Poster presentation
19. Cao WQ, Wang CS. Study on Expression of c-Ha-ras- protooncogene in psoriatic lesions. 4th Congress Asia Pacific Association of Societies of Pathologist (APASP). Beijing, China. 1995. Oral presentation.
PUBLICATIONS
1. Ren B, Zakharov V, Yang Q, McMahon L and Cao W. MACC1 is related to colorectal cancer initiation and early stage invasive growth. AJCP. In press
2. Zakharov V, Ren B, Ryan C and Cao W. Diagnostic value of HMGAs, p53 and β-catenin in discriminating adenocarcinoma from adenoma or reactive atypia in ampulla and common bile duct biopsies. Histopathology. Online publication 2013
3. Roy A, Gaylo A, Cao W, Saubermann LJ and Lawrence BP. Neither direct nor developmental exposure to bisphenol A alters the severity of experimental inflammatory colitis in mice. Journal of Immunotoxicol. 2013. Jan, 3, Epub ahead of print.
4. Cao WQ, Ma ZF, Rasenick MM, Yeh SY, and Yu J. N-3 ploy-unsaturated fatty acids shift
estrogen signaling to inhibit human breast cancer cell growth. PLoS One, 2012; 7 (12): e52838.
5. Bryant B, Maskovyak A, Schiffhauer L, Bryant R, Cao W, di Sant'Agnese P, et al. Online Teaching and Assessment Modules for Rotations in Surgical Pathology. MedEdPORTAL; 2012.
6. Yu JE, Ravin SS, Uzel G, Landers C, Targan S, Malech H, Holland S, Cao WQ, Harpaz N, Mayer L, Cunningham-Rundles C. High levels of Crohn’s disease-associated anti-microbial antibodies are present and independent of colitis in chronic granulomatous disease. Clinical Immunology, 2011, 138, 14-22.
7. Cao WQ, Adley BP, Liao J, Lin XQ, Talamonti M, Bentrem D, Rao MS and Yang GY. Mucinous nonneoplastic cyst of the pancreas: Apomucin phenotype distinguishes this entity from intraductal papillary mucinous neoplasm. Human Pathology. 2010, 41: 513-521.
8. Elkhatib E, Cao WQ, Rao MS, fryer J and Buchman A. Serum B12 concentration is elevated in patients receiving chronic parenteral nutrition, but is not a marker of parenteral nutrition associated liver disease. J Clin Gastroenterol. 2010 Sep;44(8):571-4.
9. Kelemen K, Cao WQ, Peterson LC and Variakojis D. Mediastinal Large B-Cell Lymphoma in HIV: Report of Two Cases. J Hematopathology. 2009; 2: 45-49.
10. Cao WQ, Goolsby CL, Nelson BP, Singhal S, Mehta J and Peterson LC. Instability of immunophenotype in plasma cell myeloma. American Journal of Clinical Pathology. 2008; 129: 926-933
11. Meyer K, Lee JS, Dyck PA, Cao WQ, Rao MS, Thorgeirsson SS, Reddy JK. Molecular profiling of hepatocellular carcinomas developing spontaneously in acyl-CoA oxidase deficient mice: comparison with liver tumors induced in wild-type mice by a peroxisome proliferator and a genotoxic carcinogen. Carcinogenesis. 2003; 24(5): 975-84.
12. Yu S, Matsusue K, Kashireddy P, Cao WQ, Yeldandi V, Yeldandi AV, Rao MS, Gonzalez FJ, Reddy JK. Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression. J Biol Chem. 2003 Jan 3; 278(1):498-505.
13. Meyer K, Jia Y, Cao WQ, Kashireddy P, Rao MS. Expression of peroxisome proliferators-activated receptor alpha, and PPARalpha regulated genes in spontaneously developed hepatocellular carcinomas in fatty acyl –COA oxidase null mice. Int. J Oncol. 2002 Dec; 21(6): 1175-80.
14. Misra P, Qi C, Yu S, Shah SH, Cao WQ, Rao MS, Thimmapaya B, Zhu Y, Reddy JK. Interaction of PIMT with transcriptional coactivators CBP, p300 and PBP: Differential role in transcriptional regulation. J Biol Chem, 2002
15. Cherkaoui-Malki M, Meyer K, Cao WQ, Latruffe N, Yeldandi AV, Rao MS, Bradfield CA, Reddy JK. Identification of novel peroxisome proliferator-activated receptor alpha target genes in mouse liver using cDNA microarray analysis. Gene Expr. 2001; 9(6):291-304.
16. Yu S, Cao WQ, Kashireddy P, Meyer K, Jia Y, Hughes DE, Tan Y, Feng J, Yeldandi AV, Rao MS, Costa RH, Gonzalez FJ, Reddy JK. Human peroxisome proliferator-activated receptor alpha (PPARalpha) supports the induction of peroxisome proliferation in PPARalpha-deficient mouse liver. J Biol Chem. 2001 Nov 9; 276(45):42485-9
17. Zhu Y, Qi C, Cao WQ, Yeldandi AV, Rao MS, Reddy JK. Cloning and characterization of PIMT, a protein with a methyltransferase domain, which interacts with and enhances nuclear receptor coactivator PRIP function. Proc Natl Acad Sci USA, 2001 Aug, 28; 98 (18):10380-5.
18. Cook WS, Jain S, Jia Y, Cao WQ, Yeldandi AV, Reddy JK, Rao MS. Peroxisome proliferator-activated receptor alpha-responsive genes induced in the newborn but not prenatal liver of peroxisomal fatty acyl-CoA oxidase null mice. Exp Cell Res. 2001 Aug 1; 268(1):70-6.
19. Dadras SS, Cook WS, Yeldandi AV, Cao WQ, Rao MS, Wang Z, Reddy JK. Peroxisome proliferator-activated receptor alpha-dependent induction of cell surface antigen Ly-6D gene in the mouse liver. Gene Expr. 2001; 9(4-5):173-81.
20. Kan L, Jain S, Cook W, Cao WQ, Usuda N, Yeldandi AV, Rao MS, Kanwar YS, Reddy JK. Cloning and expression of the mouse deoxyuridine triphosphate nucleotidohydrolase gene: differs from the rat enzyme in that it lacks nuclear receptor interacting LXXLL motif. Gene Expr. 1999; 8(4):231-46.
21. Cao WQ, Zhang DM, Wang CS. C-Ha-ras protooncogene and psoriasis. Chinese Journal of Dermatology. 1996, 29(2). 85-87
22. Cao WQ, Wang CS. Interleukin-1 receptor antagonist (IL-1ra) and psoriasis. Foreign Medical Science- Dermatology & Venerelogy 1997, 23(3): 152-154