Kun Jiang, MD, PhD

Curriculum Vitae for: Kun Jiang, MD, PhD

Email: Jiang.Kun@Moffitt.org

Current Position: Assistant Member

Department of Anatomic Pathology

Moffitt Cancer Center

12902 Magnolia Drive Tampa, FL 33612

813.745.8203

813.745.1708

Current Academic

Appointment: Assistant Professor

Department of Oncologic Sciences, MDC 44

Morsani College of Medicine

University of South Florida

12901 Bruce B. Downs Blvd

Tampa, FL 33612

Previous Academic

Positions:

11/04 - 6/08 Assistant Professor

Department of Molecular Medicine

University of South Florida College of Medicine

Tampa, FL

5/03 - 11/04 Assistant Professor

6/02 - 5/03 Instructor

Department of Interdisciplinary Oncology

H. Lee Moffitt Cancer Center & Research Institute

University of South Florida College of Medicine

Tampa, FL

7/98 - 6/02 Research Associate, Project Leader

Department of Interdisciplinary Oncology,

H. Lee Moffitt Cancer Center & Research Institute

University of South Florida College of Medicine

Tampa, FL

Education:

7/12 - 6/13 Gastrointestinal Pathology Fellow

Department of Pathology and Laboratory Medicine

Emory University School of Medicine

Atlanta, GA

7/11 - 6/12 Surgical Pathology Fellow

Department of Pathology and Laboratory Medicine

Emory University School of Medicine

Atlanta, GA

Kun Jiang, MD, PhD

7/08 - 6/11 Pathology Resident

Department of Pathology

Penn State Hershey Medical Center

Penn State University College of Medicine

7/1998 MD, PHD

College of Medicine

Beijing Medical University

PHD Thesis: “C-erbB-2/HER-2 anti-sense retroviral-mediated gene

therapy: suppression of malignant phenotype of human cancer cells”

Department of Biochemistry and Molecular Biology College of Medicine, Beijing Medical University

US Certifications:

 American Board of Pathology: 2011

 USMLE Step 1: 07/06/2006; result: 99% (244)

 USMLE Step 2 CK: 03/06/2007; result: 99% (244)

 USMLE Step 2 CS: 05/04/2007; result: PASS

 ECFMG Certification: 06/25/2007

 USMLE Step 3: 04/07/2008; result: 88% (213)

Research Funding History:

NIH R01 DK54393-05A2 (PI: Denise R. Cooper, PHD)

Title: Signaling regulating protein kinase C beta pre-mRNA splicing

Role: Co-PI

Annual funding: $200,000

Funding period: 4/01/08 - 3/31/13

US Government VA Merit (PI: Denise R. Cooper, PHD)

Title: Insulin regulation of protein kinase C beta gene expression and glucose uptake

Role: Co-PI

Annual funding: $125,000

Funding period: 4/01/08 - 3/31/13

Penn State University College of Medicine Research Award Title: Dissecting PI3K/Akt signaling in NSCLC Role: PI

Project funding: $8,000

Funding period: 5/01/09 - 6/30/11

Teaching Responsibilities:

Department of Anatomic Pathology, H. Lee Moffitt Cancer Center, University of South Florida, College of Medicine

7/13 - present PGY-1 to 4 residents, MS IV and Surgical Pathology Fellows

Responsibilities: Teaching Pathology during conferences, previewing and signing out

Department of Pathology, Emory University Hospital, Emory University School of Medicine

7/11 - 6/13 PGY- 1 to 4 residents, MS III and IV and Clinical GI fellows

Responsibilities: Teaching Pathology during conferences, previewing and signing out

Department of Pathology, Pennsylvania State University Hershey Medical Center

2008 - 2011 PGY-1 to 3 residents, Medical students (MS III and MS IV)

Responsibilities: Teaching medical students during their Pathology elective rotations

Department of Molecular Medicine, University of South Florida College of Medicine

2004 - 2008 Three PhD students (Eden Kleiman, Hercules A. Apostolatos, Karen Cobin)

Role: co-research mentor

Professional Organizations:

National:

 United States and Canadian Academy of Pathology (USCAP 2009 - current)

 The American Society for Clinical Pathology (ASCP 2008 - current)

 College of American Pathologists (CAP 2008 - current)

 American Society for Investigative Pathology (ASIP 2008 - 2011)

 Task Force Council, ASIP (2009 - 2011)

 American Association for Cancer Research (AACR, 2002 - 2009)

 Endocrine Society (2005 - 2010)

Regional:

 Pennsylvania Association of Pathologists (2008 - 2011)

Pennsylvania State Hershey Medical Center Committees:

 Anatomic Pathology Quality Improvement Committee (2008-2009)

 Anatomic Pathology Tissue Committee and Quality Assurance Committee (2009-2010)

 Anatomic Pathology Quality Improvement Committee (2010-2011)

Editorial Position:

 Invited Journal Reviewer (2013 - now), Open Journal of Pediatrics (OJPed)

 Editorial Intern (2009 - 2011), Laboratory Investigation, USCAP

Selected Honors and Awards:

2014 Most Outstanding Anatomic Pathology Attending, University of South Florida Department of Pathology, College of Medicine/USF Health, July 2014, Tampa, FL.

2012 Platform Oral Presentation, Quantitative monitoring of hepatic fibrosis in orthotopic liver transplant patients utilizing Image Informatics: correlation with pathologic assessment. Jiang K, Dar WA, Farris AB. American Society for Clinical Pathology annual meeting, October 2012, Boston, MA.

2010 Abraham D. Sobel 2010 ASIP Educational Fund Scholar: Akt regulates Raf/MEK/ERK cascade, VEGF and MMP expression, and malignant characteristics of NSCLC cells. Jiang K, Rice S, Sharp T, Qi J, Mu D, Han B, Zander DS. American Society for Investigative Pathology (ASIP) annual meeting, April 2010, Anaheim, CA.

2000 JOURNAL COVER: Pivotal Role of Phosphoinositide-3 Kinase in Regulation of the Cytotoxicity of Natural Killer Cells. Jiang K, et al. Nature Immunology, 2000 Vol. 1 (5):419-425. Review about this finding in the same issue.

1998 Outstanding Medical Graduate Scholarship, Beijing Medical University. Thesis, “C-erbB-2/HER-2 anti-sense retroviral-mediated gene therapy: Suppression of malignant phenotype of cancer cells”.

Selected Oral Presentations and Lectures:

1. Jiang K, Dar WA, Farris AB. Quantitative monitoring of hepatic fibrosis in orthotopic liver transplant patients utilizing digital Image analysis: correlation with pathologic assessment. American Society for Clinical Pathology annual meeting, October 2012, Boston, MA.

2. Guttenplan J, Kosinska W, Zhao ZL, Chen KM, Aliaga C, Cooper T, Sun YW, Zhang SM, Jiang K, Amin S, El-Bayoumy K. Mutagenesis and carcinogenesis induced by dibenzol [α, l] pyrene in the mouse oral cavity: A potential new model for oral cancer. American Association for Cancer Research (AACR) 101st annual meeting, April 2010, Washington, DC.

3. Jiang K, Abendroth CS. Fine needle aspiration: efficiency of on site sufficiency evaluation. Pathology Grand Rounds, Pennsylvania State Hershey Medical Center, April 2010, Hershey, PA.

4. Jiang K, Wells J. Autopsy findings in non-surgically managed Tetralogy of Fallot. Medicine Grand Rounds, Pennsylvania State University Hershey Medical Center, April 2010, Hershey, PA

5. Jiang K, Abendroth CS. Congenital Cytomegalovirus Infection. Pediatric and Neonatal Medicine Grand Rounds. Pennsylvania State Hershey Medical Center, April 2009, Hershey, PA.

6. Jiang K, Corbin KD, Patel NA, Watson JE, Cooper DR. PI-3 Kinase-, Akt- and Src tyrosine kinase-mediated regulation of CLK/STY, serine/arginine-rich protein phosphorylation and pre-mRNA splicing. Endocrinology 87th Annual Conference, June 2005, San Diego, CA.

7. Jiang K, Zhong B, Cerione RA, Wei S, Djeu JY. Critical role of PI 3-Kinase in regulation of natural killer cells. Experimental Biology 2001 Annual meeting, March 2001, Orlando, FL.

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8. Jiang K, Coppola D, Crespo NC, et al. The farnesyltransferase inhibitor, FTI-277 targets the phosphatidylinositol 3-kinase/AKT2 pathway to induce apoptosis: Molecular targets and cancer therapeutics discovery, development, and clinical validation. AACR-NCI-EORTC International Conference, November 1999, Washington, DC.

Selected Publications:

1. Jiang K, Lawson D, Cohen C, Siddiqui MT. Galectin-3 and PTEN Expression in Pancreatic Ductal Adenocarcinoma, Pancreatic Neuroendocrine Neoplasms and Gastrointestinal Tumors on Fine-Needle Aspiration Cytology. Acta Cytologica. 2014; 58:281-287.

2. Jiang K, Rankin CR, Nava P, Sumagin R, Kamekura R, Stowell SR, Feng M, Parkos CA, Nusrat A. Galectin-3 regulates desmoglein-2 and intestinal epithelial intercellular adhesion. Journal Biological Chemistry. 289: 10510-10517.

3. Shi Z, Das S, Okwan-Duodu D, Esiashvili N, Flowers C, Chen Z, Wang X, Jiang K, Nastoupil LJ, Khan MK. Patterns of failure in advanced stage diffuse large B-cell lymphoma patients after complete response to R-CHOP immunochemotherapy and the emerging role of consolidative radiation therapy. International Journal of Radiologic Oncology and Biological Physics, 2013 86:569-577

4. Chen KM, Guttenplan J, Kosinska W, Aliaga C, Cooper T, Sun YW, Jiang K, Amin S, El-Bayoumy K. Mechanisms underlying oral carcinogenesis induced by the tobacco component, dibenzo[a,l]pyrene. International Journal of Cancer 2013, 133: 1300-1309.

5. Jiang K, Wang Y, Iantosca M, Comito M, Specht C. Intracranial mesenchymal chondrosarcoma: Light and electron microscopic study of a pediatric case. Journal of Neuropathology & Experimental Neurology, 2010; 69:560.

6. Jiang K, Patel NA, Waston JE, Apostolatos AH, Kleiman E, Hanson O, Hagiwara M, Cooper

DR. Akt2 regulation of Cdc2-like kinases (Clk/Sty), serine/arginine-rich (SR) protein phosphorylation, and insulin-induced alternative splicing of PKCbetaII messenger ribonucleic acid. Endocrinology 2009; 150:2087-2097.

7. Chappell DS, Patel NA, Jiang K, Li P, Waston JE, Cooper DR. Functional involvement of protein kinase C-betaII and its substrate, myristoylated alanine-rich C-kinase substrate (MARCKS), in insulin-stimulated glucose transport in L6 rat skeletal muscle cells. Diabetologia 2009; 52:901-911.

8. Jiang K, Apostolatos AH, Watson JE, Vickers T, Cooper DR, Epling Burnette PK, Patel NA. Identification of a novel antiapoptotic human protein kinase C delta isoform, PKCdelta VIII in NT2 cells. Biochemistry 2008; 47:787-797.

9. Ghosh N, Patel NA, Jiang K, Watson J, Cheng J, Chalfant CE, Cooper DR. Ceramide-Activated Protein Phosphatase (CAPP) involvement in insulin resistance via Akt, SRp 40, and RNA splicing in L6 skeletal muscle cells. Endocrinology 2007; 148:1359-1366.

10. Donapaty S, Louis S, Horvath E, Jiang K, Sebti S, Malafa MP. RRR-alpha-tocopherol succinate down-regulates oncogenic Ras signaling. Molecular Cancer Therapy 2006; 5:309-316.

11. Jiang K, Sun JZ, Sebti S. Akt mediate Ras downregulation of RhoB, a suppressor of transformation, invasion, and metastasis. Molecular and Cellular Biology 2004; 24:5565-5576.

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12. Jiang K, Delarue F, Sebti S. EGFR, ErbB2 and Ras but not Src suppress Rho while ectopic expression of RhoB antagonizes oncogenic mediated transformation. Oncogene 2004; 13:1135-1145.

13. Dan HC, Jiang K, Coppola D, Hamilton A, Nicosia SV, Sebti S, Cheng JQ. Phosphatidylinositol-3 kinase/AKT and survivin pathways as critical targets for geranylgeranyltransferase inhibitor-induced apoptosis. Oncogene 2004; 23:706-715.

14. Zhong B, Jiang K, Gilvary DL, Epling-Burnette PK, Ritchey C, Liu J, Jackson RJ, Hong-Geller E, Wei S. Human neutrophils utilize a Rac/Cdc42-dependent MAPK pathway to direct intracellular granule mobilization towards microbial pathogens. Blood 2003; 101:3240-3248.

15. Jiang K, Zhong B, Gilvary D, Corliss B, Vivier E, Hong-Geller E, Wei S, Djeu JY. Syk regulation of PI-3 kinase for nature killer lysis. Journal of Immunology 2002; 168:3155-3164.

16. Djeu JY, Jiang K, Wei S. A view to a kill: signals triggering cytotoxicity. Clinical Cancer Research 2002; 8:636-40.

17. Jiang K, Zhong B, Ritchey C, Gilvary D, Kroeger J, Hong-Geller E, Cerione RA, Wei S, Djeu JY. Regulation of Akt-dependent cell survival by Syk and Rac. Blood 2003; 101:236-244.

18. Zhong B, Jiang K, Gilvary D, Corliss B, Burnette PK, Wei S, Djeu JY. Human neutrophils play important function in suppressing tumor cell proliferation and malignant phenotype. Immunobiology 2002; 205:74-94.

19. Epling-Burnette PK, Zhong B, Bai F, Jiang K, Bailey RD, Garcia R, Jove R, Djeu JY, Loughran TP Jr, Wei S. Cooperative regulation of Mcl-1 by Janus kinase/stat and phosphatidylinositol 3-kinase contribute to granulocyte-macrophage colony-stimulating factor-delayed apoptosis in human neutrophils. Journal of Immunology 2001; 15:7486-7495.

20. Jiang K, Zhong B, Gilvary D, Corliss B, Hong-Geller E, Cerione RA, Wei S, Djeu JY. Pivotal role of phosphoinositide-3 kinase in regulation of the cytotoxicity of nature killer cell. Nature Immunology 2000; 1:419-426.

21. Jiang K, Coppola D, Crespo NC, Nicosia SV, Hamilton AD, Sebti SM, Cheng JQ. Phosphatidylinositol 3-kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis. Molecular & Cellular Biology 2000; 20:139 – 148.

22. Wei S, Liu JH, Epling-Burnette PK, Jiang K, Zhong B, Djeu JY. IL-2 modulates lyn and MAP protein kinase activity in human neutrophils. Immunobiology 2000; 202:363 – 382.

23. Jiang K, Coppola D, Crespo NC, Nicosia SV, Hamilton AD, Sebti SM and Cheng JQ. The farnesyltransferase inhibitor, FTI-277 targets the phosphatidylinositol 3-kinase/AKT2 pathway to induce apoptosis. Clinical Cancer Research 1999; 5:3800 (supplement).

24. Jiang K, Chin YE, Tong TJ. Effect of erbB-2 repression and EGF stimulation on the level of STAT1 and cyclin D1. Journal of Beijing Medical University 1998; 30(3):205-286.

25. Jiang K, Gao L, Tong TJ. Inhibition of erbB-2 and promotion effect of EGF on p21, p53 gene transcription in vitro. Chinese Journal of Biochemistry and Molecular Biology 1999; 15(1):154-156.

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26. Jiang K, Tong TJ. The relationship between erbB-2 and the malignant phenotype as well as proliferation regulation of human gastric cancer cells. Chinese Journal of Biochemistry and Molecular Biology 1998; 14(4):457-462.

27. Jiang K, Tong TJ, Qin Y, Wang XQ, Wu M. The decline of human gastric cancer cell proliferation and responsiveness to EGF by down-regulation of c-erbB-2. Progress in Nature Science 1999; 9(4):273-278.

28. Jiang K, Chin YE, Tong TJ, Wang XQ, Wu M. Mechanism of inhibiting gastric cancer cell proliferation and its responsiveness to EGF by antisense c-erbB-2. Progress in Nature Science 1999; 9(2):145-150.

29. Wang XD, Jiang K, Wang W, Chen PL, Tong TJ. Effects of c-erbB-2 knock out on proliferation and gene expression of HeLa cells. Progress in Nature Science 1999; 9(1):72-76.

30. Wang XD, Jiang K, Wang W, Chen PL, Tong TJ. Inhibition of c-erbB-2 expression and cellular proliferation by knocking out c-erbB-2 gene in HeLa cancer cells. Chinese Progress in Cancer Research 1998; 4(1):163-166.

31. Tian Y, Jiang K, Mao Z. Effects of swim-training on the expression of myosin and actin in mice skeletal muscle. Chinese Journal of Sports Medicine 1998; 17(9):23-28.

32. Jiang K, Tong TJ, Wang XQ, et al. C-erbB-2 antisense recombinant retrovirus effectively inhibited proliferation and malignant phenotype of erbB-2-overexpression human gastric cancer cells. Chinese Progress in Cancer Research 1997; 3(1):223-225.

33. Jiang K, Tong TJ, Wang XQ, et al. Suppression of tumorigenicity of human gastric cancer cells in nude mice by c-erbB-2 antisense recombinant retrovirus. National Progress in Medical Biochemistry 1996; 2(1):48-51.

34. Jiang K, Tong TJ. Progress in research of proto-oncogene c-erbB-2. National Journal of Medical Science 1996; 27(4):56-58.

35. Wu LY, Wu AR, Jiang K. Effects of antisense c-erbB-2/HER-2 on behavior and drug sensitivity in ovarian cancer cells. Chinese Journal of Obstetrics & Gynecology 1996; 31:169-172.

Selected Abstracts:

1. Jiang K, Siddiqui M, Cohen C. Aberrantly Elevated Galectin-3 and Decreased PTEN in Fine Needle Aspirations of Pancreatic Ductal Adenocarcinoma but Not Neuroendocrine or Gastrointestinal Tumors. College of American Pathologists 2013 Annual Meeting, October 2013, Orlando, FL.

2. Jiang K, Siddiqui M, Cohen C. Aberrantly elevated Galectin−3 and carbohydrate antigen Tn expression in fine needle aspiration specimens of pancreatic ductal adenocarcinoma but not neuroendocrine tumors. United States and Canadian Academy of Pathology 2013 annual meeting, March 2013, Baltimore, MD.

3. Jiang K, Siddiqui M, Cohen C. Deregulated Mucin Carbohydrate Antigens Tn and Sialosyl−Tn: Potential Utility in Fine Needle Aspiration Specimens of Pancreas. United States and Canadian Academy of Pathology 2013 annual meeting, March 2013, Baltimore, MD.

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4. Jiang K, Siddiqui M, Cohen C. Galectin−3, STn and Tn: Expression Profile in Pancreatic Neoplasms and Gastrointestinal Stromal Tumors. United States and Canadian Academy of Pathology 2013 annual meeting, March 2013, Baltimore, MD.

5. Jiang K, Dar WA, Farris AB. Quantitative monitoring of hepatic fibrosis in orthotopic liver transplant patients utilizing digital image analysis: correlation with pathologic assessment. American Society for Clinical Pathology annual meeting, November 2012, Boston, MA.

6. Jiang K, Rice S, Sharp T, Qi J, Mu D, Han B, Zander DS. Akt associates with and modulates Raf1 signaling and malignant characteristics of NSCLC cells. American Society for Investigative Pathology annual meeting, April 2011, Washington DC.

7. Jiang K, Comito M, Specht C. A case of intracranial chondrosarcoma in a pediatric patient. Pennsylvania State Medical Center Resident/Fellow Research Day, March 2011, Hershey, PA.

8. Jiang K, Rice S, Sharp T, Qi J, Mu D, Han B, Zander DS. Akt regulates Raf/MEK/ERK cascade, VEGF MMP expression, and malignant characteristics of NSCLC cells. Pennsylvania Stat Medical Center Resident/Fellow Research Day, March 2011, Hershey, PA.

9. Chen KM, Guttenplan J, Aliaga C, Cooper T, Deltondo J, Kosinska W, Sharma AK, Sun YW, Zhang SM, Jiang K, Bruggeman R, Amin S, El-Bayoumy K. A fjord region (±)-anti-dibenzol [α, l] pyrene-11, 12-dihydrodiol-13, 14-epoxsides ((±)-anti-DB [α, l] PDE), is a powerful and specific inducer of squamous cell carcinoma in the oral cavity of mice. American Association for Cancer Research (AACR) 101st annual meeting, April 2010, Washington, DC.

10. Jiang K, Comito M, Specht C. A case of intracranial chondrosarcoma in a pediatric patient. American Association of Neuropathology annual meeting, June 2010, Washington, DC.

11. Jiang K, Rice S, Sharp T, Qi J, Mu D, Han B, Zander DS. Akt regulates Raf/MEK/ERK cascade, VEGF MMP expression, and malignant characteristics of NSCLC cells. American Society for Investigative Pathology (ASIP) annual meeting, April 2010, Anaheim, CA.

12. Jiang K, Abendroth CS. Personal commitment of residents affects the outcome of lymph node dissection, Inaugural PSHMC Resident/Fellow Research Day, April 2009, Hershey, PA.

13. Jiang K, Patel NA, Watson JE, Hagiwara M, Cooper DR. Involvement of SRPK in Insulin stimulated exon inclusion: Identification of SRp30b/SC35 as a substrate. 89th Endocrinology Conference, June 2007, Toronto, Canada.

14. Alli A, Lopez D, Jiang K, Gower W. Novel in vitro association between C-type natriuretic peptide receptor and beta-arrestins. 89th Endocrinology Conference, June 2007, Toronto, Canada.

15. Cooper DR, Patel NA, Jiang K. PI-3 Kinase-, Akt- and Src tyrosine kinase-mediated regulation of CLK/STY protein phosphorylation and pre-mRNA splicing. American Society of Biochemistry and Molecular Biology (ASBMB), April 2006, San Francisco, CA.

16. Kleiman E, Yedell Q, Jiang K, Corbin KD, Patel NA, Watson JE, Cooper DR. Insulin regulates alternative splicing of PKCβII mRNA in Hela cells: PPAR activator enhances insulin responsiveness. 87th Endocrinology Conference, June 2005, San Diego, CA.

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17. Corbin KD, Ghosh N, Jiang K, Chalfant CE, Patel NA, Watson JE, Cooper DR. De Novo ceramide synthesis mediates tumor necrosis factor -induced insulin resistance in L6 skeletal muscle cells via PP1 activation. 87th Endocrinology Conference, June 2005, San Diego, CA.

18. Jiang K, Delarue F, Sebti SM. EGFR, ErbB2 and Ras but not Src suppress RhoB expression while ectopic expression of RhoB antagonizes oncogene-mediated transformation. 95th Annual Meeting, American Association for Cancer Research, March 2004, Orlando, FL.

19. Jiang K, Sun J, Sebti SM. Akt mediates Ras downregulation of RhoB, a suppressor of transformation, invasion and metastasis. 95th Annual Meeting, American Association for Cancer Research, March 2004, Orlando, CA.

20. Jiang K, Delarue F, Sebti SM. EGFR, ErbB2, Ras and Myc suppress RhoB promoter transcriptional activity. 94th Annual Meeting, American Association for Cancer Research, April 2003, Toronto, Canada.

21. Jiang K, Zhong B, Gilvary D, Corliss B, Djeu JY. Pivotal function of Phosphatidylinositol 3-Kinase in regulation of natural killer cells. International Symposium, Molecular Basis of Immune Cell Activation and Immunological Disorders, February 2001, San Diego, CA.

22. Jiang K, Zhong B, Gilvary D, Corliss B, Hong-Geller E, Cerione RA, Wei S, Djeu JY. Critical role of PI 3-Kinase in regulation of natural killer cells. Experimental Biology 2001 Annual meeting, March 2001, Orlando, FL.

23. Jiang K, Djeu JY. Mapping the signal pathways in non-specific effector cells. New Molecular Targets for Cancer Therapy, October 2000, St. Petersburg, FL.

24. Wei S, Zhong B, Gilvary G, Burnette PK, Jiang K, Djeu JY. Defining the role of MAPK in controlling granule mobilization in human neutrophils. New Molecular Targets for Cancer Therapy, October 2000, St. Petersburg, FL.

25. Sebti SM, Jiang K, Coppola D, Crespo NC, Nicosia SV, Hamilton AD, Cheng JQ. FTI-277, a farnesyltransferase inhibitor induces apoptosis by blocking the phosphatidylinositol 3-Kinase/AKT2 survival pathway in human cancer cells. 91st Annual Meeting, American Association for Cancer Research, April 2000, San Francisco, CA.

26. Cheng J Q, Jiang K, Coppola D, Crespo NC, Nicosia SV, Hamilton AD, Sebti SM. The phosphoinositide 3-OH Kinase/AKT2 pathway as a critical target for farnesyltransferase Inhibitor-induced apoptosis. 91st Annual Meeting, American Association for Cancer Research, April 2000, San Francisco, CA.

27. Jiang K, Coppola D, Crespo NC, Nicosia SV, Sebti SM, Cheng JQ. Phosphatidylinostol 3-kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced Apoptosis. 15th International Meeting on Oncogene and Tumor Suppressors, June 1999, Frederick, MD.

28. Jiang K, Coppola D, Crespo NC, Nicosia SV, Hamilton AD, Sebti SM, Cheng JQ. The farnesyltransferase inhibitor, FTI-277 targets the phosphatidylinositol 3-kinase/AKT2 pathway to induce apoptosis. Molecular Targets and Cancer Therapeutics Discovery, AACR-NCI-EORTC Conference, November 1999, Washington, DC.

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29. Jiang K, Tong TJ, Wang XQ, Wu M. Relationship between the down-regulation of ErbB-2 expression and the proliferation control of human gastric cancer cells. 4th National Conference on Cancer Research, May 1998, Guangzhou, China.

30. Wang XD, Ren QH, Chen PL, Jiang K, Tong TJ. Effects of HER-2 gene targeting. 4th National Conference on Cancer Research, May 1998, Guangzhou, China.

31. Jiang K, Tong TJ, Wang XQ, Wu M. Inhibition of proliferation and tumor malignant phenotype by antisense c-erbB-2 retrovirus in human breast and gastric cancer cells. 3rd National Conference on Cancer Research, June 1996, Hang Zhou, China.

32. Jiang K, Tong TJ, Wang XQ, Wu M. Suppression of tumorigenicity of human gastric cancer cells in nude mice by c-erbB-2 antisense retrovirus. 2nd National Conference in Oncology and Molecular Biology, October 1996, Beijing, China.