Curriculum Vitae for: Haipeng Shao, M.D., Ph.D.

Date: May 2014

Current Position: Assistant Member

Hematopathology and Laboratory Medicine

Moffitt Cancer Center

12902 Magnolia Drive

Tampa, FL 33612

(813)-745-2672 (Office)

(813)-679-4091 (Cell)

(813)-745-1708 (Fax)

Haipeng.Shao@moffitt.org

Current Academic Appointments:

Assistant Professor

Department of Oncologic Sciences, MDC 44

College of Medicine

University of South Florida

12901 Bruce B. Downs Blvd.

Tampa, FL 33612

Education:

1994 - 2000: Doctor of Philosophy (Ph.D)

Biochemistry

Department of Molecular and Cellular Biochemistry

University of Kentucky

Lexington, KY 40536

1988 - 1993: Doctor of Medicine (M.D.)

West China University of Medical Sciences

Chengdu, Sichuan, P.R. China 610041

Postgraduate Training and Fellowship Appointments

2008 - 2010 Fellowship

Hematopathology

National Cancer Institute, National Institutes of Health

Bethesda, MD 20892

2004 - 2008 Residency

Anatomic and clinical pathology

Department of Pathology & Laboratory Medicine

University of Wisconsin Hospital and Clinics

Madison, WI 53792

2003 - 2004 Postdoctoral Fellow

Department of Physiology and Neuroscience

Medical University of South Carolina

Charleston, SC 29425

2000 - 2003 Postdoctoral Associate

Department of Genetics

Yale University

New Haven, CT 06510

Employment:

1993 -1994: Clinical Pathologist

The Fifth Affiliated Hospital of Zhengzhou University

Zhengzhou, Henan, China 450052

Licenses

Wisconsin State Medical License (48992-020), 2006, Status: Active.

Florida State Medical License (ME 106987), 2010, Status: Active.

Board Certifications:

2009 Board Certified in Hematology, by American Board of Pathology

2008 Board Certified in AP/CP, by American Board of Pathology

2003 ECFMG Certificate (0-637-973-9)

Languages Spoken

English, Chinese.

Teaching Experience

1. University Courses

8/2005 – 9/2005 Pathology 703

Role: Instructor to Medical Students

University of Wisconsin Medical School, Madison, WI

2. Teaching and Training Experience:

02/05/2013 HIV-related Lymphoproliferative Disorders

1 hour lecture

01/25/2014 Sclerosing angiomatoid nodular transformation of spleen

Spleen Case Conference

10/09/2013 NK cell leukemia/lymphoma

1 hour lecture

09/2013 Pathology lab

Role: Instructor to Second year Medical Students, 2x3 hours

Department of Pathology, College of Medicine

University of South Florida, Tampa, FL

04/15/2013 NK cell leukemia/lymphoma

1 hour lecture

04/09/2013 T/NK-cell lymphomas

2 hours lecture

12/03/2012 Primary cutaneous B-cell lymphoma

1 hour lecture

09/14/2012 Unknown Lymphoma Conference

1 hour teaching

Role: training for Hematopathology fellows and residents

Moffitt Cancer Center, Tampa, FL

09/2012 Pathology lab

Role: Instructor to Second year Medical Students, 3x3 hours

Department of Pathology, College of Medicine

12/05/2011 Reactive lymphadenopathy, Part 2

1.5 hour lecture

11/28/2011 Reactive lymphadenopathy, Part 1

1.5 hour lecture

09/2011 Pathology lab

Role: Instructor to Second year Medical Students, 3x3 hours

Department of Pathology, College of Medicine

University of South Florida, Tampa, FL

05/10/2011 Peripheral T-cell lymphomas

3 hours lecture

Role: training lecture for Hematopathology fellow and residents

Moffitt Cancer Center, Tampa, FL

02/2011 Gamma-Delta T-cell lymphomas

Role: training lecture for Hematopathology fellow and residents

Moffitt Cancer Center, Tampa, FL

09/2010 Pathology lab

Role: Instructor to Second year Medical Students, 3x3 hours

Department of Pathology, College of Medicine

University of South Florida, Tampa, FL

06/2006 Flow Cytometry for Angevine Fellows.

Role: Instructor to Medical Students

University of Wisconsin Hospital and Clinics, Madison

01/2006 Urinary tract anatomy, histology and pathology

Role: Instructor to Medical Technology Students

Wisconsin State Laboratory of Hygiene, Madison, WI

Honors and Awards

1. Chief Resident awarded at the University of Wisconsin Hospital and

Clinics, Madison, WI 53792. 2007-2008

2. Postdoctoral Fellowship awarded by the American Heart Association.

Award Number: 0120278T (Rank: 6.73%), $ 64,000. 2001-2003

Research Support

Pending

External Grants:

Account #: MCC 16749

Name of PI: Haipeng Shao, M.D.

Funding Source: NIH

Dates: 12/01/2013-11/30/2015

Source: NIH

Title: Detection of Somatic Mutation using MutS Protein and next

generation sequencing.

% Effort: 25

Role in the Study: PI

Total Direct Costs: $ 275,000

Total Amount of Award: $ 463,375

Date Submitted: 02/16/2013

Preliminary Score if available: N/A

Clinical Trial:

Account #: MCC 17024

Name of the PI: Lubomir Sokol

Dates: 3/13/13 to 3/13/18

Source: Seattle Genetics

Title: Brentuximab vedotin in patients with relapsed/refractory diffuse

large B cell lymphoma of elderly.

% Effort: N/A

Role in the Study: Co-PI, Pathologist

Total Direct Costs: $250,000

Total Amount of Award: $250,000

Professional Association Memberships

2010-present Member, American Society for Clinical Pathology

2010-present Member, United States & Canadian Academy of Pathology

2012-present Member, Society for Hematopathology

2014 Member, College of American Pathologists

Peer-Reviewed Publications

1. Wu H, Zhang L, Shao H, Sokol L, Sotomayor E, Letson D, Bui MM.

Prognostic significance of soft tissue extension, International Prognostic

Index, and multifocality in primary bone lymphoma: a single institutional

experience. Br J Haematol. 2014 Mar 27.

2. Zhang L, Shao H. Primary cutaneous CD4 positive small/medium

T-cell lymphoma with high proliferation index and CD30-positive large lymphoid

cells. J Cutan Pathol. 2013 Aug;40(8):720-4. PMID: 23672694.

3. Zhang X, Sun M, Zhang L, Shao H. Primary hepatosplenic CD5-positive

diffuse large B-cell lymphoma: a case report with literature review. Int J Clin

Exp Pathol. 2013 Apr 15;6(5):985-9. PMID: 23638236

4. Shao H, Calvo KR, Grönborg M, Tembhare PR, Kreitman RJ,

Stetler-Stevenson M, Yuan CM. Distinguishing hairy cell leukemia variant from

hairy cell leukemia: Development and validation of diagnostic criteria. Leuk

Res. 2013 Apr;37(4):401-9. PMID: 23347903

5. Zhang L, Sotomayor EM, Papenhausen PR, Shao H, Moscinski LC,

Sandin RL, Caceres G, Valenica H, Malafa M, List AF, Sokol L. Unusual

concurrence of T-cell large granular lymphocytic leukemia with Franklin disease

(gamma heavy chain disease) manifested with massive splenomegaly. Leuk

Lymphoma. 2013 Jan;54(1):205-208. PMID: 22694793.

6. Setoodeh R, Schwartz S, Papenhausen P, Zhang L, Sagatys EM, Moscinski

LC, Shao H. Double-hit mantle cell lymphoma with MYC gene rearrangement

or amplification: a report of four cases and review of the literature. Int J

Clin Exp Pathol. 2013;6(2):155-67. PMID: 23330001

7. Setoodeh R, Zhang L, Shao H. Concurrent splenic diffuse red pulp

small B-cell lymphoma and benign clonal proliferation of T-cell large granular

lymphocytes. Leuk Res. 2012 Mar; 36(5):e103-106. PMID: 22385871

8. Setoodeh R, Peker D, Feldman AL, Law ME, Zhang L, Moscinski LC, Shao

H. Secondary Hairy Cell Leukemia in a Patient with Chronic Myelogenous

Leukemia Following Treatment with Tyrosine Kinase Inhibitors: Report of an

Extremely Rare Case and Review of the Literature. J Med Cases 2012

Feb;3(1):39-42

9. Shao H, Xi L, Raffeld M, Feldman AL, Ketterling RP, Knudson R,

Rodriguez-Canales J, Hanson J, Pittaluga S, Jaffe ES. Clonally related

histiocytic/dendritic cell sarcoma and chronic lymphocytic leukemia/small

lymphocytic lymphoma: a study of seven cases. Mod Pathol. 2011 Nov;

24(11):1421-32. PMID: 21666687

10. Shao H, Xi L, Raffeld M, Pittaluga S, Dunleavy K, Wilson WH,

Spector N, Milito C, Morais JC, Jaffe ES. Nodal and extranodal plasmacytomas

expressing immunoglobulin a: an indolent lymphoproliferative disorder with a

low risk of clinical progression. Am J Surg Pathol. 2010 Oct;34(10):1425-35.

PMID: 20871216.

11. Shao H, Yuan CM, Xi L, Raffeld M, Morris JC, Janik JE,

Stetler-Stevenson M. Minimal residual disease detection by flow cytometry in

adult T-cell leukemia/lymphoma. Am J Clin Pathol. 2010 Apr;133(4):592-601.

PMID: 20231613.

12. Spencer ML, Shao H, Andres DA. Induction of neurite extension

and survival in pheochromocytoma cells by the Rit GTPase. J Biol Chem. 2002 Jun

7;277(23):20160-8. PMID: 11914372.

13. Spencer ML, Shao H, Tucker HM, Andres DA. Nerve growth

factor-dependent activation of the small GTPase Rin. J Biol Chem. 2002 May

17;277(20):17605-15. PMID: 11877426.

14. Finlin BS, Gau CL, Murphy GA, Shao H, Kimel T, Seitz RS, Chiu

YF, Botstein D, Brown PO, Der CJ, Tamanoi F, Andres DA, Perou CM. RERG is a

novel ras-related, estrogenregulated and growth-inhibitory gene in breast

cancer. J Biol Chem. 2001 Nov 9;276(45):42259-67. PMID: 11533059.

15. Rusyn EV, Reynolds ER, Shao H, Grana TM, Chan TO, Andres DA,

Cox AD. Rit, a nonlipid-modified Ras-related protein, transforms NIH3T3 cells

without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways. Oncogene. 2000

Sep 28;19(41):4685-94. PMID: 11032018.

16. Shao H, Andres DA. A novel RalGEF-like protein, RGL3, as a

candidate effector for rit and Ras. J Biol Chem. 2000 Sep 1;275(35):26914-24.

PMID: 10869344.

17. Finlin BS, Shao H, Kadono-Okuda K, Guo N, Andres DA. Rem2, a

new member of the Rem/Rad/Gem/Kir family of Ras-related GTPases. Biochem J.

2000 Apr 1; 347 Pt 1:223-31. PMID: 10727423.

18. Shao H, Kadono-Okuda K, Finlin BS, Andres DA. Biochemical

characterization of the Rasrelated GTPases Rit and Rin. Arch Biochem Biophys.

1999 Nov 15; 371(2):207-19. PMID:10545207.

19. Andres DA, Shao H, Crick DC, Finlin BS. Expression cloning of a

novel farnesylated protein, RDJ2, encoding a DnaJ protein homologue. Arch

Biochem Biophys. 1997 Oct 1;346(1):113-24. PMID: 9328291.

Scientific Abstracts/Poster Presentations/Plenary Presentations:

1. Johnny Nguyen, Haipeng Shao. CD30 expression is associated with

worse prognosis in adult T-cell leukemia/lymphoma. Poster presented at United

States & Canadian Academy of Pathology (USCAP) Meeting; March 2014, San

Diego, CA.

2. Reza Setoodeh, Haipeng Shao, Dahui Qin, Lynn Moscinski, Maryam

Tahmasbi, Mojdeh Naghashpour, Ling Zhang, and Kenian Liu. FISH Analysis of

Blastic Plasmacytoid Dendritic Cell Neoplasm for 9p21.3 Deletion. Poster

presented at United States & Canadian Academy of Pathology (USCAP) Meeting;

March 2013, Baltimore, MD.

3. Setoodeh R, Shao H. Double-Hit Mantle Cell Lymphoma: Review Of 3

Cases of Blastoid Mantle Cell Lymphoma With C-myc Overexpression. Poster

presented at CAP 2012 meeting, San Diego, CA. IJCEP, January 2013

4. Setoodeh R, Zhang L, Shao H. An unusual splenic diffuse red pulp

small B-cell lymphoma with a coexistent clonal proliferation of large

granulocytic T-lymphocytes (T-LGLs): report of a rare case. Poster presented

at: College of American Pathologists (CAP) Meeting; September 11-14, 2011;

Grapevine, TX. Leukemia Research, May, 2012.

5. Setoodeh R, Shao H, Messina J, Naghashpour M. An unusual case of

blastic plasmacytoid dendritic cell neoplasm with recurrence as a nasal polyp:

a case report and review of the literature. Poster presented at: College of

American Pathologists (CAP) Meeting; September 11-14, 2011; Grapevine, TX.

6. Haipeng Shao, Liqiang Xi, Mark Raffeld, Andrew Feldman, Rhett

Ketterling, Ryan Knudson, Jaime Rodriguez-Canales, Jeffrey Hanson, Stefania

Pittaluga and Elaine Jaffe. Chronic lymphocytic leukemia/small lymphocytic

lymphoma with transformation to histiocytic/dendritic cell sarcoma: alterations

of 17p as a potential risk factor. United Sates and Canadian Academy of

Pathology, 100th Annual

Meeting, 02/2011, San Antonio, TX. Platform presentation (abstract number:

451989).

7. Haipeng Shao, Marlene Grönborg, Constance Yuan, Robert Kreitman

and Maryalice Stetler-Stevenson. Hairy Cell Leukemia and Variant:

Immunophenotypic Comparison and Variations. United Sates and Canadian Academy

of Pathology, 100th Annual

Meeting, 02/2011, San Antonio, TX. Poster presentation (abstract number:

452455).

Service

Synoptics Working Group

The Infection Control Committee

Lymphoma Pathways Workgroup

Served as reviewer for professional journals:

Thoracic Cancer, Laboratory Investigation, Experimental Hematology,

Archives of Pathology & Laboratory Medicine, North American Journal of

Medical Sciences.

Served as reviewer for external grants:

Research Council KU Leuven in 05/2013 on grant “Setup of an in vivo

platform for personalized treatment in agressive B-cell non-Hodgkin lymphoma.”