PERSONAL INFORMATIONS:

First name:SOUFIANE

Last name:EL HALLANI

Citizenship:Canada, Morocco

Current appointment:

• Anatomical Pathology

The Ottawa Hospital

Ottawa, Ontario, Canada

• Co-founder and Scientific Lead
  

MAROCPATH Technologies s.a.r.l

Casablanca, Morocco

Former appointment:

• Research Fellow

British Columbia Cancer Agency

Vancouver, British Columbia, Canada

• Internship

Assistance Publique – Hopitaux de Paris

Paris, France

Scheduled appointment

• Clinical Fellow

          Molecular Genetic Pathology

          University of Pittsburgh Medical Centre (UPMC)

EDUCATION AND DEGREES:

Pre-University Education:

Victor Hugo International College, Marrakesh, Morocco

High-school Diploma, speciality “Physic-Chemistry”

1999

University Education:

University Cadi Ayyad, Marrakech, Morocco

Medical Doctor

1999 – 2006

University of Pierre et Marie Curie, Paris, France

Master 1, Human Genetics and Molecular Biology

2004 – 2006

Postgraduate Education:

University of Paris XII, Val-De-Marne, France

Master 2, Surgical science – oncology

2006 – 2007

Institut Gustave Roussy, Paris, France

PhD program, Oncology and Cancer Biology

2007 – 2009

Simon Fraser University, Vancouver, British Columbia, Canada

Post-doctoral Research Fellowship

2009 – 2011

University of Ottawa, Ontario, Canada

Anatomical Pathology Residency Program

2011 – 2016

University of Pittsburgh Medical Centre, Pennsylvania, USA

Molecular Genetic Pathology Fellowship

2016 – 2017

MEMBERSHIP:

Association of Molecular Pathologist, 2014

United State and Canada Academy of Pathology, 2011-2015

Canadian Association of Pathologists, 2012-2015

European Society of Pathology, 2012-2015

American Physician-Scientist Association (APSA), 2009-2013

Public Relation Committee, APSA, 2012-2013

AWARD AND DISTINCTIONS:

Award:

Nadia Michael Research Award 2012

Nadia Michael Research Award 2014

Prize:

Association de Recherche sur les Tumeurs Cérébrales (ARTC) 2006

Ligue Contre le Cancer 2007 – 2009

Marrakech School of Medicine prizewinner 2002 and 2003

MEDICAL LICENSURE:

License of Medical Council of Canada (LMCC), 2012

TEACHING:

Assistant in undergraduate medical education “Pathology Lab”

University of Ottawa (2012-present)

English and French class

LANGUAGES :

English, French, Arabic, Darija (and conversational Spanish)

PUBLICATIONS:

Book chapter:

El Hallani S and Ratbi I. Familial Gliomas: Role of TP53 gene. Tumors of the central nervous system. Springer. Union, NJ.

Preparation:

Submitted:

D. El Demellawy, S. El Hallani, J. de Nanassy, E. Chan, J. Bass, D. Mack, A. Nasr.

Predictive value of a histopathological grading system for complicated ileo-anal anastomosis (J-pouch) procedure in children with refractory ulcerative colitis.

S. El Hallani, E.D. Euscher, A.A. Roma, E.J Moschiano, R. Ali-Fehmi, E.E. Frauenhoffer, D.P. Montiel, I. Kim, S.R. Hong, D. Barbuto, A. Malpica and E.G. Silva, B. Djordjevic.

Frozen Section Does Not Reliably Predict the Likelihood of Lymph Node Involvement in Early Stage Endometrioid Cancer of the Endometrium: toward a new paradigm shift?

I. Ahmed, S. El Hallani, K.T. Mai and S. Islam.

Cytologic features of thyroid lesions diagnosed as indeterminate for neoplasia which predict follicular neoplasm on fine needle aspiration biopsy of thyroid (FNAB): a 5 year retrospective study in a tertiary care hospital in Ontario, Canada.

S. El Hallani, C. Poh, S. Hakim, P. Lane, D. Gravel, C. Parra-Herran, S. Robertson, S. Islam.

Direct Autofluorescence Visualization to guide Breast specimen grossing: A Proof-Of-Concept.

El Hallani S, Morley C, Islam S.

The use of static images for proficiency testing in gynaecologic cytopathology: A proposal with simulation and short cases.

Canadian Journal of Pathology.

Published: S. El Hallani, M. Guillaud, J. Korbelik, C.E. Marginean. Evaluation of Quantitative Digital Pathology in the assessment of Barrett’s Esophagus associated Dysplasia. American Journal of Clinical Pathology 2015. E-pub ahead of print. El Hallani S, Colin C, El Houfi Y, Idbaih A, Boisselier B, Marie Y, Ravassard P, Labussière M, Mokhtari K, Thomas JL, Delattre JY, Eichmann A, Sanson M. Tumor and endothelial cell hybrids participate in glioblastoma vasculature. Biomed Res Int. 2014;2014:827327.

El Hallani S, Poh CF, Macaulay CE, Follen M, Guillaud M, Lane P. Ex vivo confocal imaging with contrast agents for the detection of oral potentially malignant lesions. Oral Oncol. 2013 Jun; 49(6):582-90.

P. Moretto, V.J. Nair, S. El Hallani, S. Malone, E.C. Belanger, C. Morash, C. Canil. Management of penoscrotal extramammary Paget’s disease: case-series and review of literature.

Current Oncology 2013; 20(4).

El Hallani S, Rossetto M, Sanson M. The Pro/Pro genotype at TP53 codon 72 polymorphism is associated with early onset glioblastoma. Cancer Genet. 2012 Dec; 205(12):677.

McAlpine JN, El Hallani S, Lam SF, Kalloger SE, Luk M, Huntsman DG,

MacAulay C, Gilks CB, Miller DM, Lane PM.

Autofluorescence imaging can identify preinvasive or clinically occult

lesions in fallopian tube epithelium: a promising step towards screening

and early detection. Gynecologic Oncology 2011 Mar; 120(3):385-92.

Sierra Del Rio M, Ricard D, Houillier C, Navarro S, Gonzalez-Aguilar A, Idbaih A, Kaloshi G, Elhallani S, Omuro A, Choquet S, Soussain C, Hoang-Xuan K. Prophylactic intrathecal chemotherapy in primary CNS lymphoma. J Neurooncol. 2012 Jan; 106(1):143-6.

El Hallani S, Boisselier B, Peglion F, Rousseau A, Colin C, Idbaih A, Marie Y, Ravassard P, Mokhtari K, Thomas JL, Delattre JY, Eichmann A, Maniotis A, Sanson M.

A new alternative mechanism in glioblastoma vascularization: tubular vasculogenic mimicry. Brain 2010 Apr; 133(Pt 4):973-82.

Ngwabyt Bikeye SN, Colin C, Marie Y, Vampouille R, Ravassard P, Rousseau A, Boisselier B, Idbaih A, Calvo CF, Leuraud P, Lasalle M, El Hallani S, Delattre JY, Sanson M.

ASPM-associated stem cell proliferation is envolved in malignant progression of gliomas and constitutes an attractive therapeutic target. Cancer Cell International 2010 Jan 11; 10:1.

Labussiere M, Idbaih A, Wang XW, Marie Y, Blandine B, Falet C, Paris S, Laffaire J, Carpentier C, Criniere E, Ducray F, El Hallani S, Mokhtari K, Hoang-Xuan K, Delattre JY, Sanson M.

All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2.

Neurology 2010 Jun 8; 74(23):1886-90.

Ducray F, El Hallani S, Idbaih A.

Diagnostic and prognostic markers in gliomas.

Current Opinion in Oncology 2009 Nov; 21(6): 537-42.

Sanson M, Marie Y, Paris S, Idbaih A, Laffaire J, Ducray F, El Hallani S, Boisseler B, Mokhtari K, Hoang-Xuan K, Delattre JY.

Isocitrate dehydrogenase 1 (IDH1) codon 132 mutation is an important prognostic biomarker in gliomas.

Journal of Clinical Oncology 2009 Sep; 27(25): 4150-4.

Shete S, Hosking FJ, Robertson LB, Dobbins SE, Sanson M, Malmer B, Simon M, Marie Y, Boisselier B, Delattre JY, Hoang-Xuan K, El Hallani S, Idbaih A, Zelenika D, Andersson U, Henriksson R, Bergenheim AT, Feychting M, Lönn S, Ahlbom A, Schramm J, Linnebank M, Hemminki K, Kumar R, Hepworth SJ, Price A, Armstrong G, Liu Y, Gu X, Yu R, Schoemaker M, Muir K, Swerdlow A, Lathrop M, Bondy M, Houlston RS.

Genome-wide association study identifies six susceptibility loci for glioma.

Nature Genetics 2009 Aug; 41(8): 899-904.

Boisselier B, Marie Y, El Hallani S, Kaloshi G, Iershov A, Kavsan V, Psimaras D, Thillet J, Hoang-Xuan K, Delattre JY, Sanson M.

No association of (-131C-->G) variant of CHI3L1 gene with risk of glioblastoma and prognosis.

Journal of Neuro-Oncology 2009 Sep; 94(2): 169-72.

El Hallani S, Ducray F, Idbaih A, Marie Y, Boisselier B, Colin C, Navarro S, Chinot O, Thillet J, Hoang-Xuan K, Delattre JY, Sanson M.

TP53 codon 72 polymorphism is associated with age of onset of glioblastoma.

Neurology 2009 Jan; 72(4): 332-6.

El Hallani S, Boisselier B, Marie Y, Paris S, Idbaih A, Carpentier C,Hoang-Xuan K, Delattre JY, Sanson M.

TP53 mutations but no CHEK2 *1100DelC variant in familial gliomas.

Cancer Genetics and Cytogenetics 2009 Jan; 188(2):126-8.

Idbaih A, Boisselier B, Marie Y, Sanson M, El Hallani S, Crinière E, Fourtassi M, Paris S, Carpentier C, Rousseau A, Mokhtari K, Combadière C, Laigle-Donadey F, Hoang-Xuan K, Delattre JY.

Influence of MDM2 SNP309 alone or in combination with the TP53 R72P polymorphism in oligodendroglial tumors.

Brain Research 2008 Mar; 1198:16-20.

Idbaih A, Boisselier B, Marie Y, El Hallani S, Sanson M, Crinière E, Rodero M, Carpentier C, Paris S, Laigle-Donadey F, Ducray F, Hoang-Xuan K, Delattre JY.

TP53 codon 72 polymorphism, p53 expression, and 1p/19q status in oligodendroglial tumors.

Cancer Genetics and Cytogenetics 2007 Sep; 177(2):103-7.

El Hallani S, Marie Y, Boisselier B, Idbaih A, Ducray F, Delattre JY, Sanson M.

No association of MDMD2 SNP309 with risk of glioblastoma and prognosis.

Journal of Neuro-Oncology 2007 Dec; 85(3): 241-4.

Platform Presentation:

Poster Abstract:

S. El Hallani, H. El Attar, D. Garner, C.E. Marginean, S. Islam, H. Sekhon.

Pathologist goes to work: Affordable automation for cervical cancer screening in developing countries.

United States and Canada Academy of Pathology (USCAP) 2014, San Diego, March 2014.

S. El Hallani, C. Colin, B. Boisselier, Y. Marie, J.Y. Delattre, M. Sanson.

The tumor cell who wanted to be an endothelial cell. ANOCEF congress, Lyon (France), June 2009.

S. El Hallani.

Vascular plasticity of glioblastoma stem cells. Institut Gustave Roussy research day, Roscoff (France), May 2009.

S. El Hallani, B. Boisselier, A. Idbaih, J.Y. Delattre, M. Sanson.

Genetic polymorphims of the P53 pathway in glioblastoma. ANOCEF congres, Toulouse (France), May 2007.

S. El Hallani, E, Belanger, N. Schieda, K.T. Mai, T. Flood.

Predictors of tumor upgrading or upstaging after radical prostatectomy in patients with Gleason score 3+4 prostate cancer (PCa) at transrectal ultrasound (TRUS) guided needle biopsy.

United States and Canada Academy of Pathology (USCAP) 2015, Boston, March 2015.

S. El Hallani, C. Poh, S. Hakim, P. Lane, D. Gravel, S. Robertson, S. Islam.

Direct Autofluorescence Visualization to guide Breast specimen grossing: A Proof-Of-Concept.

United States and Canada Academy of Pathology (USCAP) 2014, San Diego, March 2014.

S. El Hallani, P. Milman, J. Woulfe.

Intranuclear rodlet depletion in pancreas of diabetes patient.

United States and Canada Academy of Pathology (USCAP) 2013, Baltimore, March 2013.

Invited Guest Speaker:

B. Djordjevic, S. El Hallani, E.D. Euscher, A.A. Roma, E.J Moschiano, R. Ali-Fehmi, E.E. Frauenhoffer, D.P. Montiel, I. Kim, S.R. Hong, D. Barbuto, A. Malpica and E.G. Silva.

Frozen section does not reliably predict the likelihood of lymph node involvement in early endometriod endometrial cancer.

United States and Canada Academy of Pathology (USCAP) 2012, Vancouver, March 2012.

El Hallani S, Martial Guillaud, Jagoda Korbelik, Celia Esmeralda Marginean.

Quantitative tissue phenotype as a new diagnostic test for Barrett’s Esophagus.

World Congress on Gastrointestinal Cancer, Barcelona, June 2012.

S. El Hallani, M. Guillaud, D. Owen, I. Tai and C. MacAulay.

Can changes in tissue architecture of the rectum be used for the early detection of colon cancers?

Canadian Digestive Disease Week, Vancouver, February 2011.

S. El Hallani, Pierre Lane, Calum MacAulay.

In vivo confocal imaging of human epitheliums: which contrast agent to use?

BiOS 2011-Endoscopic Microscopy. San Francisco, January 2010

S. El Hallani, Sylvia Lam, Jessica McAlpine, Blake Gilks, Calum MacAulay, Pierre Lane.

Utility of fallopian tube imaging techniques for Tubal Intraepithelial Carcinoma detection.

BiOS 2011-Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues. San Francisco, January 2010

S. El Hallani.

“Pathologist goes to work: Affordable automated cervical cancer screening for Africa”

7th Stop Cervical Cancer in Africa, July 2013, Maputo, Mozambique African First Ladies against Breast and Cervical Cancer, Princess Nikky Breast Cancer Foundation and Africa-America Cancer Consortium

S. El Hallani.

Understanding Health Advocacy through Actions: Cervical Cancer Screening in Developing Countries.

Canadian Association of Pathologists, Toronto, July 2014