现任奥兰多地区医院病理科主治医生且主管住院医生训练。

南佛州及佛州州立大学医学院兼职（副）教授
80—85年  西安四军大医学系
85—87年  西安四军大病理系研究生（刘彦仿教授及王文亮教授为导师）
87—91年  美国南加州大学博士后及Ph.D学生
91—96年  俄亥俄州大学医学院病理系住院医生
96—98年  约翰霍普金斯大学医学院消化及肝脏病理fellow
98—02年  佛蒙特大学医学院病理主治医生（且兼）助理教授
02—现在   现职

专长：普通病理；消化道及肝脏病理；住院医生培养及训练（管理）

SHUAN C. LI, M.D.
 
Current Appointment                        Attending Pathologist and Residency Director
 
Adjunct Appointment                        Affiliate Assistant Professor, University of South Florida & Florida State University
              
Business Address                               Department of Pathology and Laboratory Medicine
                                                                Orlando Regional Medical Center
                                                                1414 South Orange Ave.
                                                                Orlando, FL 32806
                                                                Phone (407) 841-5217
                                                                FAX   (407) 843-2447
                                                                E-mail: shuanli@orhs.org
 
Education
 
1980-1985                                    M.D.
                                                        The Fourth Military Medical University
                                                                Xian, Shaanxi, P. R. China
                                                               
1985-1987                                    M. Sc.     
                                                        The Fourth Military Medical University
                                                                 Xian, Shaanxi, P. R. China
                                                               
1989-1991                                    Ph.D. Candidate in Biochemistry and Molecular Biology
                                                        Graduate School, University of Southern California
                                                        Los Angeles, California
                                                      
1997-1998                                    Executive Graduate Certificate
                                                        Business of Medicine Program, School of Continuing Studies
                                                        The Johns Hopkins University
                                                        Baltimore, Maryland
 
Professional Experience
 
1984-1985                                    Internship
                                                        Xijing Hospital
                                                        The Fourth Military Medical University
                                                        Xian, Shaanxi, P. R. China
 
 
1987-1988                                    Fellowship in Molecular Pathology
                                                        Department of Pathology
                                                        LAC-USC Medical Center and School of Medicine
                                                        Los Angeles, California
                                                        Mentors: Drs. W. John Martin and Clive R. Taylor
 
1988-1989                                    Fellowship in Molecular Biology and Biochemistry
                                                        Department of Biochemistry and Norris Comprehensive Cancer Center
                                                        University of Southern California School of Medicine
                                                        Los Angeles, California
                                                        Mentor: Dr. Amy S. Lee
 
 
1991-1995                                    Resident in Anatomic and Clinical Pathology
                                                        The Ohio State University Medical Center
                                                        Columbus, Ohio
 
1995-1996                                    College of American Pathologists Foundation Fellowship
                                                        The Ohio State University Medical Center
                                                        Columbus, Ohio
                                                        Mentor:  Dr. Karl S. Theil
 
1996-1997                                    Fellowship in Gastrointestinal and Liver Pathology
                                                        The Johns Hopkins Hospital and School of Medicine
                                                        Baltimore, Maryland
                                                        Mentors: Drs. Stanley R. Hamilton, John H. Yardley, John K. Boitnott
 
1997-1998                                                                  Staff Pathologist
                                     The Johns Hopkins Hospital
                                     Johns Hopkins University
                                                        Baltimore, Maryland
 
1998-2001                                    Assistant Professor and Attending Pathologist
                                                        University of Vermont/Fletcher Allen Hearth Care
                                                        Burlington, Vermont
 
Academic and Hospital Appointments
 
1991-1996                            Clinical Instructor in Pathology
                                                The Ohio State University, Columbus, Ohio
 
1995-1996                            Clinical Specialist in Pathology
                                                Riverside Methodist Hospitals, Columbus, Ohio
 
1996-1997                            Clinical Fellow in Pathology
                                                The Johns Hopkins University and School of Medicine
                                                Baltimore, Maryland
 
1997-1998                            Assistant Staff Pathologist
                                                The Johns Hopkins University and School of Medicine
                                                Baltimore, Maryland
 
1998-2001                            Assistant Professor and Attending Pathologist
                                                University of Vermont/Fletcher Allen Hearth Care
                                                Burlington, Vermont
 
2000-2001                            Assistant Professor of Medicine (Gastroenterology & Hepatology)
                                                University of Vermont/Fletcher Allen Hearth Care
                                                Burlington, Vermont
 
University & Hospital Committees
 
                                               Research Committee: Department of Pathology, University of Vermont
 
                                               Senate: University of Vermont
 
                                               Faculty Review Committee: Department of Pathology, University of Vermont
 
 
 
Teaching Experience
                                       
                                        Medical Students Pathology Labs (July 1991-June 1997)
                                        Gastroenterology Grand Rounds (weekly, July 1996- June 1997)
                                        Surgical Oncology Grand Rounds (monthly, July 1997-June 1997)
                                        Gastroenterology-Pathology Conference (weekly, July 1998-present)
                                        General Surgery-Pathology Conference (bi-weekly, July 1998-presnet)
                                        Pathology 302, Gastrointestinal Pathology (October, 1998, 1999, 2000, 2001)
                                        Pathology 302 Labs (September 1998-November 1998, 1999, 2000, 2001)
                                        School of Cytotechology, FAHC (January 1999, 2000)
 
Grants and Funding
 
Mawe GM, Sharkey KA, Moses PL, Li SC (Co-Investigator)
Mechanisms of Neuroimmune Integration in the Colon.
Dept. of Health and Human Services, March 22, 1999 (not approved,  resubmitted March 2001)
 
Li, SC (PI): Differential Expression of b-Catenin and MMP-7 in High-grade colorectal adenomas with true- and pseudo-invasion using Laser Capture Microdissection technique.  Submitted for 2001 Kimmel Scholar Award.
 
Zvara P, Li, SC (C0-Investivator): Chemoablation in the treatment of localized prostatic cancer.  Submitted for DOD Grant, March 2001
 
Licensure                    
 
                                        ECFMG  433-039-5 (October 3, 1991)
                                        Ohio (Temporary License: 0008842, July 1, 1991-June 30, 1996)
                                        Pennsylvania MD-055629-Y (exp. December 31, 2000)
                                        Maryland  D0052166 (exp. September 30, 2000)
                                        Vermont 042-0009683 (exp. November 30, 2000)
                                        Maine TD-00-86 (temporary, is. 8/7/2000, exp.12/31/2000)
                                        Florida ME 83966 (is. 12/22/2001)
 
Board Certification
                                      
                                        American Board of Pathology
                                        (Anatomic and Clinical Pathology, November 8, 1995)         
 
Professional Societies     
 
                                        College of American Pathologists: 1991-1998, 2000-present
                                        International Academy of Pathology: 1998-present
                                        Vermont Medical Society: 1998-2002  
                                        American Society of Clinical Pathology: 1991-1998
                                        American Society of Investigative Pathology: 1994-1996
                                        American Medical Association: 1992-1995
                                        Ohio Society of Pathologists: 1995-1996
                                        Central Ohio Society of Pathologists: 1991-1996
                                                      
Awards and Honors          
 
                                        Student of the Year Award (five times) 1981-1985
 
                                        CAP Stipend Recipient for Concepts in Molecular Pathology Workshop
                                        Bethesda,  Maryland. April 1993
 
                                        College of American Pathologists Foundation Fellowship
                                        July 1, 1995- June 30, 1996
 
                                        Finalist, Third Annul Resident Competition, Ohio Society of Pathologists     
                                        Columbus, Ohio.  May 1996
 
Professional Presentations
 
                Regional:
 
                            The prevalence and etiology of macrocytosis:
                            a study of 3,500 patients.
                            Presented at the First Annual Pathology Research Day, The Ohio State University
                            Columbus,  Ohio.  April 1994
 
Dual-color fluorescence in situ hybridization for detecting the t(X;18)(p11.2;q11.2) associated with synovial sarcoma in interphase and metaphase nuclei.
                            Presented at the Ohio Valley Regional Cytogenetic Conference
                            Cincinnati, Ohio.  May 1996
 
Molecular cytogenetics of synovial sarcoma: Applications in surgical pathology.
                            Presented at the Third Annual Resident Competition, Ohio Society of Pathologists.
Columbus, Ohio.  May 1996
 
                            Autoimmune Hepatitis, a case presentation.
                            Presented at Pediatric Grand Rounds.
                            Burlington, VT. November 1998
 
                            Autoimmune hepatitis, a case presentation.
                            Presented at the Green Mountain Gut Club.
                            Waterberry, Vermont  May 1999
 
                            The pathology of Celiac disease.
                            Presented at the Green Mountain Gut Club
                            Killington, Vermont December 1999
 
                            Diagnosing inflammatory bowel disease in colonoscopic biopsies: Is it possible?
                            Pathology Grand Rounds, University of Vermont
                            Burlington, Vermont January 2000
 
National:
 
Dual-color fluorescence in situ hybridization for detecting the t(X;18)(p11.2;q11.2) associated with synovial sarcoma in interphase and metaphase nuclei.
                            Presented at the CAP/ASCP Spring Meeting.  Boston,  MA.  April 1996
                          
Dual-color fluorescence in situ hybridization for detecting the t(X;18)(p11.2;q11.2) associated with synovial sarcoma in interphase and metaphase nuclei.
                            Presented at the 21st Annual Meeting, Association of Cytogenetic technologists
                            Norfolk, VA.  June 1996
 
Malignancy involving the rectum may manifest as solitary rectal ulcer syndrome.
                            Annual USCAP meeting, Orlando, FL.  March 1997.
 
The histopathology of the terminal ileum in lymphocytic and collagenous colitis.
Annual USCAP meeting. New Orleans, LA.  March  2000
 
Mib-1 reactivity and p16 expression in 45 pleomorphic adenomas and 10 carcinomas of the parotid gland with clinicopathologic correlation.
Annual USCAP meeting.  Atlanta, GA. March 2001
 
Cytokeratin 7 and 20 Expression in Rectal Adenomas, Rectal Adenocarcinomas, Anal Glands, and Junctional Rectal Mucosa.
Annual USCAP meeting.  Atlanta, GA. March 2001
 
The histopathology and significance of Barrett's metaplasia; the histopathology of Sprue and IBD.
The Stowe Conference on Digestive Diseases: A Comprehensive Update in Gastroenterology and Hepatology.  March 2001
 
                International
Pathology training in the US.  Invited lecture.  301 General Hospital and the Fourth Military Medical University.  Beijing and Xian, China May 2000
 
Diagnosing IBD in colonoscopy biopsy specimens.  2000 International Academic Meeting Hua-Xia Medicine.  Zhuhai, China  May 2000
 
Recent progress in the diagnosis of inflammatory bowel disease.  Grand Rounds, The Fourth Military Medical University.  Xian, China.  May 2000
 
Mib-1 reactivity and p16 expression in 45 pleomorphic adenomas and 10 carcinomas of the parotid gland with clinicopathologic correlation.  Annual IAP meeting, Nagoya, Japan.  October 2000
 
Diagnostic pitfalls of colonic adenomatous polyps. The Fourth Military Medical University.  Xian, China.  October  2000
 
Pathology training in the US, and the diagnostic pitfalls of colonic adenomatous polyps.  Invited lectures, The Second  Military Medical University.  Shanghai, China.  October  2000
 
Hospital management in the US and China.
International Academic Meeting Hua-Xia Medicine. Hong Kong. March 2001
 
 
Community Services
 
                            Volunteer.  Orchard Elementary School of South Burlington. VT.  July 2000-present
                            ("Blood test ABC", one hour lecture to the second grader class, January 2001)
 
Publications
 
      1.       Li X, Wang WL, Liu YF: Fibronectin and human liver cirrhosis. J the 4th Military Medical University 1987; 87:185-186.
 
      2.       Li X, Wang WL, Liu YF: The location of fibronectin in human cirrhotic hepatocytes. Chinese J Pathology 1988;17(2): 124-126.                                                              
 
      3.       Li X, Warren DW, Gregoire J, Pedersen RC, Lee AS: The rat 78,000 dalton glucose-regulated protein (GRP78) as a precursor for the rat steroidogenesis-activator polypeptide (SAP): the SAP coding sequence is hom, , , , , ologous with the terminal end of GRP78. Molecular Endocrinology 1989; 3:1944-1952.
 
      4.       Li X, Lee AS: Competitive inhibition of a set of endoplasmic reticulum protein genes (GRP78, GRP94, and ERp72) retards cell growth and lowers viability after ionophore treatment. J Molec Cell Biology 1991; 11:3446-3453.
 
      5.       Li LJ, Li X, Ferrario A, Rueker N, Liu ES, Wong S, Gomer CJ, Lee AS: Establishment of a Chinese hamster ovary cell line that expresses GRP78 antisense transcripts and suppresses A23187 induction of both GRP78 and GRP94. J Cell Physiol 1992; 153:575 582.
 
6.         Li SC, Hamilton SR: Malignant tumors in the rectum simulating solitary rectal ulcer       syndrome in endoscopic biopsy specimens. Am J Surg Pathol 1998; 22: 106-112.
 
7.          Li SC, Lucas JG, Theil KS: Dual-color fluorescence in situ hybridization for detecting the t(X;18)(p11.2;q11.2) associated with synovial sarcoma in interphase and metaphase nuclei. (in preparation)
 
8.          Zvara P, Li SC, Karpman E, Plante MK: Transurethral Intraprostatic Ablation of Bovine and Canine Prostates with Ethanol. J Urology, accepted for publication,  2001
 
9.          Scully KA, Li SC, Hebert JC, Trainer TD: The Characteristic Appearance of Non-alcoholic Duct Destructive Chronic Pancreatitis:  A report of two cases. Arch Pathol Lab Med . 2000; 124:1535-1538
 
10.       Rogers FB and LI, SC: Acute colonic necrosis associated with Kayexalate enemas in a critically ill patient: Case report and review of the literature.  J. Trauma  2001 51 (2): 395-7
 
11.       Kanter, AS, Hyman NH and Li, SC: Ganglioneuromatous polyposis: a premalignant condition? a case report and review of the literature. Diseases of the Colon & Rectum. 2001 Apr; 44(4):591-3. Review.
 
12.       Zvara P, Li SC, Karpman E, Plante MK: Chemoablation of the prostate using transurethral injection of absolute ethanol-Experimental study. Endoskopie. 2000; 9:43-46
 
13.       Li, SC: Pathologic diagnosis and differential diagnosis of inflammatory and inflammatory-like diseases of the intestinal tract in endoscopic biopsies.  Review. Current Diagnostic Pathology. 2000; 6:206-212
 
14.       Saleem, G. Li, SC. MacPherson, B R. Cooper, SM. Hepatitis with interface inflammation and IgG, IgM, and IgA anti-double- stranded DNA antibodies following infliximab therapy: comment on the article by Charles et al Arthritis Rheum. 2001 44 (8): 1966-8
 
15.       Alexander J, Watanabe T, Wu T-T, Rashid A, Li S and Hamilton SR.  Histopathogical identification of colon cancer with microsatellite instability.  American Journal of Pathology 158:527-535, 2001.
 
16.       Vijayalakshmi Padmanabhan, Peter W. Callas, Shuan C. Li, and Thomas D. Trainer Histopathological Features of the Terminal Ileum in Lymphocytic and Collagenous Colitis: A Study of 32 Cases and Review of Literature. Mod. Pathol. 2003 16: 115-119.
 
17.       Li, SC; Burgart, L: Histopathology of Serrated Adenoma, Its Variants, and Differentiation From Conventional Adenomatous and Hyperplastic Polyps. Arch Pathol Lab Med. 2007;131:440–445
 
 
Book Chapters
        
"Pathology of Gastrointestinal Disease" in Essentials of Pathology, Edited by D. G. Bostwick, MD and L. Cheng, MD. Humana, 2002
 
       
Abstracts
 
      1.       Li S, Wang WL, Liu YF: Immunocytochemical location of fibronectin in cirrhotic hepatocytes on formalin-fixed and paraffin-embedded tissue sections. J Histochem Cytochem 1988; 36:939.
 
      2.       Li SC, Lucas JG, Theil KS: Dual-color fluorescence in situ hybridization for detecting the t (X;18)(p11.2;q11.2) associated with synovial sarcoma in interphase and metaphase nuclei. Cancer Genet Cytogenet 1997; 98:167.
 
3.           Li SC, Hamilton SR: Malignancy involving the rectum may manifest as solitary rectal ulcer syndrome. Modern Pathology 1997; 10:59A.
 
4.           Akbar T, Vecchio J, Moses P, Grace C, Olin J, Li SC: Primary esophageal lymphoma involving proximal esophagus in a patient with AIDS, first reported case.  American College of Gastroenterology 64th Annual Scientific Meeting.  October 1999, Phoenix, AZ
 
5.           Padmanabhan VJ, LI SC, Trainer T: The histopathology of the terminal ileum in patients with lymphocytic and collagenous colitis.  Laboratory Investigation 2000; 80:86A.  89th Annual Meeting of USCAP.  March 2000, New Orleans, LA
 
6.           Zvara Peter, Li Shuan, Karpman Edward, and Plante Mark:  Transurethral intraprostatic ablation of bovine and canine prostates with ethanol.  XVth Congress of European Association of Urology. April 2000, Brussels, Belgium
 
7        Moes, G. S., Koh, J., Beatty, B. G., and Li, S.C: Mib-1 reactivity and p16 expression in 45 pleomorphic adenomas and 10 carcinomas of the parotid gland with clinicopathologic correlation.  USCAP 2001 Annual Meeting. Modern Pathology 2001;14 (1) 152A.
 
7.           Li, SC Waters, B L, Simmons-Arnold, L, and Beatty, B.G: Cytokeratin 7 and 20 Expression in Rectal Adenomas, Rectal Adenocarcinomas, Anal Glands, and Junctional Rectal Mucosa. USCAP 2001 annual Meeting. Modern Pathology 2001; 14 (1) 90A.
 
8.       T. Bollinger, R. Lenington, J. Savell, CS. Li. A “Second Look” Improves the Yield of Lymph Nodes in Colorectal Cancer Resection Specimens.  Accepted for Presentation, College of American Pathologists Annual Meeting, October 1, 2007.
 
9.           T. Bollinger, R. Lenington, J. Savell, CS. Li. Evaluating Lymph Nodes in Colon and Rectal Cancer Resection Specimens: The Effect of a Routine "Second Look" on Patient Prognosis    American Society of Colon and Rectal Surgeons Annual Meeting, June 5, 2007.