汪键

武汉兰丁医学高科技有限公司技术总监,为兰丁公司创始人之一。汪键博士一直从事细胞病理研究,拥有细胞DNA检测分析仪及配套设备等多项专利,发表论文30余篇。

【教育经历】

1978年-1982年  同济医科大学就读于同济医科大学并获学士学位,之后留校任教;

1985年-1988年  就读于同济医科大学并获硕士学位;

1990年-1994年  在澳大利亚Monash大学从事博士研究;

1994年-1998年  在美国纽约洛克菲勒大学从事博士后研究;

1998年-2001年  在加拿大UBC大学任研究员;

2001年至今  任武汉兰丁医学高科技有限公司技术总监。

【学术文章及专著

1.  张薇,汪键,程越清等:全自动细胞图像分析仪在胸腹腔积水诊断中的应用。中国癌症杂志,2011,21:303-307

2.  牛晓泉,李芹,车东媛,汪键,孙小蓉:Ki67免疫组织化学定量分析在宫颈鳞状上皮内瘤变病理分级中的应用。华中科技大学学报(医学版),2010,39:562-564

3.  鲍琳,孙小蓉,黄怡琨,李耀辉,汪键,车东媛:用DNA倍体分析与常规细胞学结合方法进行宫颈癌普查的研究。武汉大学学报(医学版),2007,28:107-110

4.  屠庆年,汪键,车东媛,孙小蓉:非倍体细胞测定在宫颈上皮内瘤变分级中的意义。临床与实验病理杂志,2007,23:235-236

5.  孙小蓉、车东媛、涂洪章、李丹、汪键:细胞DNA倍体分析评估宫颈上皮内瘤变。中华肿瘤杂志,2006,28:831—835。

6.  汪庆林、周厚纶、李黎、汪键、孙小蓉:DNA倍体分析系统在乳腺包块针吸细胞学诊断中的应用。华中科技大学学报(医学版),2006,35:542-544

7.  孙小蓉、汪键:DNA定量细胞学。湖北科技出版社,2006 (专著)

8.  孙小蓉、汪键、Alfred Boecking:DNA倍体分析系统用于宫颈癌及上皮瘤变的诊断及预测。中华病理学杂志,2005,34:435-437

9.  Sun XR, Wang J, Garner D, Palcic B:Detection of cervical cancer and high grade neoplastic lesions by a combination of liquid-based sampling preparation and DNA measurement using automated image cytometry. Cell Oncology, 2005, 27:33-41

10.  X R Sun, Jian Wang and B Palcic. Improved Detection of Cervical Cancer and High Grade Neoplastic Lesions by a Combination of Liquid-Based Sampling Preparation and DNA Measurements Using Automated Image Cytometer. Submitted to Cellular Oncology.

11.  Jian Wang, Poonam Sethi and J.H.McNeill. Comparison of in vivo basal and insulin stimulated MAP kinase activities in Wistar and Zucker rats. In preparation.

12.  A Mohammad, Jian Wang and J.H. McNeill. Bis(maltolato)ovovanadium(IV) inhibits the activity of PTP1B in Zucker rat skeletal muscle in vivo. Molecular and Cellular biochemistry, 229:125-128 (2002).

13.  Jian Wang, V.G.Yuen and J.H.McNeill.  Effect of vanadium on insulin and leptin in Zucker diabetic fatty rats. Molecular and Cellular Biochemistry. 218:93-96 (2001).

14.  Jian Wang, V.G. Yuen and J.H.McNeill. Effects of vanadium on insulin sensitivity and appetite.  Metabolism. 50 (6):667-673 (2001).

15.  孙小蓉、刘燕、汪键、车东媛:荧光纤维支气管镜用于肺癌早期定位诊断的进展。中华结核和呼吸杂志,2001,24:309-310

16.  Jian Wang,  J.T.Alexader, P, Zheng, J.T. Dourmashikin and S.F.Leibowitz. Ovarian steroids, hypothalamic galanin and control of eating behavior and body weight in female rats. Submited to J Neuroscience.

17.  Jian Wang, Dourmashkin JT, Yan R and S.F.Leibowitz. Rapid changes in hypothalamic neuropeptide Y produced by carbohydrate-rich meals that enhance corticosterone and glucose levels. Brain Res. 848: 124-136 (1999).

18.  Jian Wang, A.Akabayash, J. T. Dourmashikin, H.J.Yu, J.T.Alexader, H.J. Chae and S.F.Leibowitz. Neuropeptide Y in relation to carbohydrate intake, corticosterone and dietary obesity. Brain Research. 802: 75-88 (1998).

19.  Jian Wang,  A.Akabayash, J. T. Dourmashikin, H.J.Yu, J.T.Alexader, I. Silva, J. Lighter Chae and S.F.Leibowitz. Hypothalamic galanin: control by signals of fat metabolism. Brain Research. 804: 7-20 (1998).

20.  Jian Wang, J.T.Alexader, P. Zheng, H.J.Yu, J. T. Dourmashikin and S.F.Leibowitz. Behavioral and endocrine traits of obesity-prone and obesity-resistant rats on macronutrient diets. American J Physiology. 278 (6 pt 1): E1057-1066 (1998).

21. S.F.Leibowitz, A. Akabayashi, J.T.Alezander and Jian Wang. Gonadal steroids and hypothalamic galanin and neuropeptide Y: role in eating behavior and body weight control in female rats. Endocrinology. 139: 1771-1780 (1998).

22.  S.F.Leibowitz, A. Akabayashi and Jian Wang. Obesity on a high-fat diet: role of hypothalamic galanin in neurons of the anterior paraventricular nucleus projecting to the median eminence. J Neuroscience. 18: 2709-2719 (1998).

23.  M.P.Hedger, Jian Wang, H.Y.Lan, R.C.Atkins and N.G.Wreford. Immunoregulatory activity in adult rat testicular interstitial fluid: relationship with intratesticular CB8+ lymphocytes following treatment with ethane dimethane sulfonate and testosterone. Biology of Reproduction. 58: 935-942 (1998).

24.  Jian Wang and K.L.Leibowitz. Central insulin inhibits hypothalamic galanin and neuropeptide Y gene expression and peptide release in intact rats. Brain Research. 777: 231-236 (1997).

25.  S.F.Leibowitz and Jian Wang. Circulating leptin effects on brain peptides involved in eating and body weight regulation. Obesity Research. 4(Suppl): 1 (1996).

26.  Jian Wang, N.G.M. Wreford, H,Y,Lan, R. Atkins and M.P.Hedger. Leukocyte populations of the adult rat testis following removal of the Leydig cells by treatment Ethane Dimethane Sulfonate and subcutaneous testosterone implants. Biology of Reproduction. 51: 551-561 (1994).

27.  Jian Wang, C.G.Zhu and W.Y.Ma. The origin of enkephalin nerve fibers in the cerebellar cortex. Acta Tongji Medical University. 20: 28-30 (1991).

28.  C.G.Zhu and Jian Wang. Catecholaminergic innervation of hypothalamic arcuate nucleus with electron microscopic cytochemical study. Acta Anatomy. 20: 373-376 (1990).

29.  Jian Wang and C.G.Zhu. Afferent projections from serotoninergic neurons of the brain stem to the cerebellar cortex in rats. Neuroanatomy. 5: 61-66 (1989).

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