王焕友老师，目前任职于加州大学圣地亚哥卫生系统和医学院，担任病理科和穆尔斯癌症中心的血液病理学副主任，血液病理培训项目主任，病理学教授。擅长淋巴造血系统良恶性疾病的综合性评估，尤其擅长淋巴瘤和白血病，目前的研究方向是淋巴瘤和和白血病的分子学和遗传学发病机制，尤其擅长使用先进的分子遗传学工具，不仅揭示淋巴瘤和白血病的发病机制，还能识别新的分子学和遗传学靶点，为精准医疗服务。

Huan-You Wang

Professor of Pathology

Director, Hematopathology Fellowship Program

Co-Director of Hematopathology

Department of Pathology and Moores Cancer Center

University of California San Diego Health System and School of Medicine

3855 Health Sciences Drive

La Jolla, CA 92093-0987, USA

Websites:

pathology.ucsd.edu/faculty/wang.htm

https://www.researchgate.net/profile/Huan-You_Wang

Expertise and Clinical Interests

My clinical expertise is within the domain of comprehensive diagnostic

evaluation of malignant and benign hematolymphoid disorders with an emphasis on lymphomas and leukemias. As an experienced hematopathologist, I utilize cytomorphology in conjunction with immunohistochemistry, in situ hybridization, flow cytometry, genetics and molecular tools to establish accurate diagnosis of lymphomas and leukemias. I welcome the opportunity to work with you on your interesting and challenging cases; I hope you could share them with me.

For more information on my clinical profiles, please visit: pathology.ucsd.edu/faculty/wang.htm

Research Interests

My current research interests focus on the underlying molecular and genetic

mechanisms of lymphomas and leukemias. I am particularly interested in the decoding of  the genetics of lymphoma and leukemia by employing advanced genetic tools such as Next Generation Sequencing (NGS) and array-based comparative genomic hybridization (aCGH). By using these robust and high throughput tools, we can not only uncover the pathogenesis of lymphomas and leukemias, but also we identify novel molecular and genetic targets for novel and personalized medicine of the 21st century.

With a PhD in Molecular Pathology and Cellular and Molecular Medicine from the University of California San Diego (UCSD), one of the top 15 research universities worldwide, I have extensive training in modern cellular and molecular bio-medical sciences, and I have a track record of publications including publication in some of the finest journals such as Cell, Molecular Cell, PNAS, and Nature. As of today, I have more than 68 published articles, which are cited more than 1148 times with total impact factor of 336.07 as of December 2015.  I welcome the opportunity to solicit more funding and collaborations to support more research endeavors in the near future.

For more information on my research profiles, please visit: https://www.researchgate.net/profile/Huan-You_Wang

Academic Faculty Positions/Titles

07/2013- present  Clinical Professor Department of Pathology, UCSD Health Sciences and

School of Medicine, La Jolla, CA

4/2009-6/2013  Associate Clinical Department of Pathology, UCSD Health Sciences and

Professor School of Medicine, La Jolla, CA

07/2005-3/2009  Assistant Professor Department of Pathology, University of Texas South-

Western Medical Center at Dallas, Dallas, TX

08/92-12/92  Assistant Professor Department of Pathology, and Affiliated Third Hospital,

Peking University, Beijing, China

09/90-08/92    Instructor Department of Pathology and Affiliated Third Hospital,

Peking University, Beijing, China

Hospital Privileges:

04/09-Present  Staff Hematopathologist UCSD Health System, University of California

San Diego, La Jolla, CA

06/09-present  Attending Physician VA San Diego Healthcare System, San Diego.

07/05-03/09 Staff Hematopathologist     University of Texas Southwestern Medical  Center at Dallas, Dallas, TX

07/05-03/09 Staff Hematopathologist     Parkland Hospital and Health System (PHHS),     Dallas, TX

07/05-03/09 Staff Hematopathologist     Children’s Medical Center of Dallas, Dallas, TXAcademic Positions held Other Than UCSD Healthcare System

7/2011-present Honorary Professor of Pathology, Binzhou Medical University, Yantai, Shandong Province, China

12/2015-12/18 Honorary Professor of Pathology, Huazhong University of Sciences and Technology, Wuhan, China

Education

Date Institution Field/Specialty Degree

08/1994-06/2000 University of California Mol Pathology/ PhD

San Diego (UCSD), USA Cellular & Molecular

Medicine

09/1987-06/1990 Tongji Medical University Experimental

Wuhan, P. R. China Pathology

09/1982-07/1987 Binzhou Medical College Medicine MD

Binzhou, P. R. China

PhD Thesis

Wang HY. Function and phosphorylation regulation of the SR family of splicing factors. PhD Dissertation. 2000.

Publication Number: AAT 9970656. ISBN: 9780599757042.

Document URL: http://roger.ucsd.edu/record=b4149113~S9

Residency and Fellowship

Date Institution Field/Specialty Program Director

07/04-06/05 University of Pennsylvania Hematopathology Jay Hess, MD PhD

& Children’s Hospital of

Philadelphia, PA

Service Chief         Virginia LiVolsi, MD

07/00-06/04 University of Virginia, VA Pathology (Anatomic Mark R. Wick, MD

Service Chief & Clinical Pathology) Stacey E. Mills, MD

Awards and Honors

05/2013 Clinical Pathology Teacher of the Year 2012-2013, Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA

1/2011 Who’s Who in Science and Engineering 2011-2012 Edition by The Marquis

Who’s Who. Eleventh Edition.

04/2009 Certificate of Appreciation, the College of American Pathologists (CAP).

Research and Funding

11/2012 Co-principal investigator of Clinical and Genomic for Prognosis of AIDS

Primary Effusion Lymphoma

NCI-UCSD: total budget: $129,000.00)

6/2011 Research Publication Seed Award, Department of Pathology,

University of California San Diego School of Medicine, La Jolla, CA

Total budget: $10,000.0

05/2010 Co-principal Investigator of A Translational Study of the mTOR Signaling

Pathway in AIDS Defining Malignancies,

NCI-UCSD: total budget: $335,328.00

09/2008 Clinical Developmental Project Award, Department of Pathology, UT South-

Western Medical Center at Dallas, Dallas, TX

Total budget: $2000.0

09/97-08/98 National Cancer Institute (NCI) Cancer Cell Biology Training Grant, NCI,

National Institutes of Health (NIH), Cellular and Molecular Medicine, UCSD.

research experience

Date Institution Field/Interests Advisor

09/87-07/90 Tongji Medical University Experimental Pathology      DN Chen

12/92-07/94 University of California at Pulmonary hypertension      Colin Bloor &

San Diego (UCSD)      Kenneth Moser

08/94-06/00 UCSD Alternative mRNA      Xiang-Dong Fu

splicing & T-cell development

Board Certification

Date Specialty State/Organization

09/23/2005 Hematology American Board of Pathology

07/26/2004 Anatomic Pathology American Board of Pathology

Clinical Pathology American Board of Pathology

Medical Licensure

Date Specialty State/Organization

02/03/2006 Certified Physician Texas Medical Board

03/12/2004 Certified physician Medical Board of California

ECFMG Certificate

Certificate No. 0-573-261-5

Initial validation 10/27/1999

Permanent validation 09/12/2002

Memberships in Professional Society

Date Membership Society/Organization

08/05 Fellow (FCAP) College of American pathologists (CAP)

08/04 Fellow (FASCP) American Society for Clinical Pathology

(ASCP)

07/01 Member College of America Pathologists (CAP)

Activities in the National Professional Society

Member, College of American Pathologist (CAP) Market Research Panel

Executive member (2015-2017), Chinese American Pathologists Association (CAPA).

Invited Talks

9/19/2015 Recent Advances in the molecular diagnosis of lymphoid malignancies.第二届同济国际临床病理研讨会暨肿瘤分子病理诊断应用及进展国际研讨会。 2015年9月19-20. 武汉，中国。

8/24/2015     Utility of Immunohistochemistry in the diagnosis and differential diagnosis of hematolymphoid malignancy. New York, New York, USA

11/2013 Histiocytic and dendritic neoplasm: the story behind trans-dedifferentiation. First Annual San Diego Society of Hematopathology, La Jolla, CA.

8/2011 ALK-1 positive lymphoma. UCSD/VA Hematopathology Interesting Conference for SAM Accreditation.

7/1/2011 Diagnostic Utility of Flow Cytometry in Hematolymphoid Malignancy. Binzhou Medical University, Binzhou, Shandong Province, China.

4/2010 Erythroblastic sarcoma presenting as bilateral ovarian masses in an infant with pure erythroid leukemia. Genoptix Medical Laboratory, Carlsbad, CA in conjunction with San Diego Hematopathology Interesting Group.

12/2008 ALK1-positive neoplasia: from lymphoma to sarcoma. Department of Pathology, Peking University Health Sciences Center, Beijing. China

5/1/2008 Notch1 in T-acute lymphoblastic leukemia. Department of Pathology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX.

Other Professional Activities

5/11/2013 Participant of the Pyramid Pathologist Accrual Workshop Study C05013: An open-label, randomized, phase 2 study to assess the effectiveness of R-CHOP with or without VELCADE in previously untreated patients with non-germinal center B-cell like large B-cell lymphoma.  San Francisco, CA

5/18/2011 Participant of the Pyramid Pathologist Accrual Workshop, New York,NY

5/25/2011 Certified Hematopathologist by Millennium Clinical Trial

07/2011 Test Contributor for Pathologist Recertification Individualized Self-Assessment Examination (PRISE), American Society for Clinical

Pathology (ASCP).

Teaching experience

Date Title Subject Institution

04/09-Present: Associate Clinical SOM 214 School of Medicine, UCSD

Professor

03/2011 Associate Clinical Problem-based School of Medicine, UCSD

Professor Learning/Hematology

07/05-03/2009 Assistant Professor Pathology UT Southwestern Medical

Center at Dallas

07/04 – 06/05 Lab Instructor Hematopathology University of Pennsylvania

07/00 – 06/04 Lab Instructor Hematopathology University of Virginia

8/92- 12/92 Assistant Professor Pathology   Beijing University

08/90 -07/92 Instructor Pathology   Peking University

09/87 -06/90 Lab Instructor Pathology   Tongji Medical University

Administrative Duties

07/12-Present Director. Hematopathology Fellowship Program, Department of

Pathology, University of California San Diego, La Jolla.

04/09-Present Co-Director Hematopathology, Department of Pathology, University of

California San Diego, La Jolla.

10/07-03/09 Director Molecular Genetic Pathology Fellowship Program

06/06-03/09 Director Hematology and Bone Marrow Laboratory, Parkland

Hospital & Health System, Dallas. UT Southwestern Medical Center at Dallas

06/06-03/09 Coordinator Hematology Fellow Hematopathology Rotation

05/06-06/07 Coordinator Pathology Resident/Medical students

07/05-07/06 Member Residency Curriculum Sub-Committee

Department of Pathology, UT Southwestern Medical Center at Dallas

Services to Department, School of Medicine and Community

7/2015- present Member, UCSD Health System Cancer Committee

4/2009-present Member, Committee for Pathology Research Lecture Series (PRLS), Department of Pathology, UC San Diego

7/2013-present Member, UCSD Credential Committee, UCSD Health System

5/2010-2013 Member, Committee for Department of Pathology Telepathology

5/2011-2015 Member, Committee Quality Service Delivery (QSD) Committee, Department of pathology, UC San Diego

10/2011-6/2014 Member, Elective Committee, School of Medicine, UC San Diego

6/2011-06/2013 Member, Clinical Resource Committee, UC San Diego Health System

02/04/2011 Judge for San Diego Unified High School District Science Fair, National Middle High School, National City, CA 91950

Publications

Articles

(Total of 62 publications with total 1101 citations and total impact factor of 336.07 as of Dec 8, 2015).

(*denotes corresponding author)

1. Wang HY and Thorson JA. T-cell primary effusion lymphoma with pseudo-monoclonal rearrangements for immunoglobulin heavy chain. Blood. 2015;126:1856

2. Nguyen JC, Kubik MJ, Broome HE, Curtin PT, Dell’Aquila ML, Wang HY*. Successful treatment of both double minute of C-MYC and BCL-2 rearrangement containing large B-cell lymphoma with subsequent unfortunate development of therapy-related acute myeloid leukemia with t(3;3)(q26.2;q21). Pathology: Research & Practice. 2015 (in press).

3. Wang L, Aghel A, Peterson BLT, Wang-Rodriguez J, Wang HY, and Zhao XF. Richter transformation with c_MYC overexpression: report of three cases. International Journal of Clinical and Experimental Pathology. 2015 (in press).

4. Wang HY*, McMahon C, Ali S, Young L, Yekezare S, Ross J, and Ball E. Novel FNDC3B and EVI1 fusion and WT1 L378fs* 7 frameshift mutation in an acute myeloid leukemia with cytomorphologic and immunophenotypic features reminiscent of acute promyelocytic leukemia.  Br J Haematol. 2015. Doi: 10.1111/bjh.13552. PMID: 26147192

5. Wang L, Peters JM , Fuda F, Li L, Karandikar NJ, Koduru P, Wang HY, Chen W. Nodal involvement by marginal zone B-cell lymphoma harboring t(14;22)(q32;q11) involving immunoglobulin heavy chain and light chain lambda as the sole karyotypically recognizable abnormality in a patient with systemic lupus erythematosus. Cytometry B Clinical Cytometry. 2014; DOI: 10.1002/cytob.21198.

6. Li K, Johnson RL, Li S, Thorson JA, Mulroney CM, Dell’Aquila ML, Wang HY*. Nodal involvement by marginal zone B- cell lymphoma harboring t(14;22)(q32;q11) involving immunoglobulin heavy chain and light chain lambda as the sole karyotypically recognizable abnormality in a patient with systemic lupus erythematosus. Int J Clin Exp Pathol. 2014;8:5221-5231.

7. Moshrefi S, Saad A, Minoo P, Wang HY, Tenenhaus M. Primary cutaneous gamma/deltaT-cell lymphoma and hemaphagocytic syndrome. Ann Plast Surg. 2014 July 4 (Epub ahead of print). DOI: 10. 10/ASP 0000000000000165. PMID: 25003465.

8. Zhang X, Liang Y, Wang HY. Invasive ductal carcinoma of the breast associated with extensive melanin melanosis: a case report and review of the literature.  Int J Clin & Exp Pathol. 2014;7:1218-1223. PMID: 24696740.

9. Yan M, Dong Z, Zhao F, Chauncey T, Deauna-Limaya D, Wang-Rodriguez J, Liu D, Wang HY, Pilz R. CD20-positive plasmablastic lymphoma with excellent response to bortezomib combined with rituximab. Eur J Haematol. 2014;93:77-80.

10.  Johnson RL, Boisot S, Ball ED, Wang HY*. A case of interdigitating dendritic cell sarcoma/histiocytic sarcoma--a diagnostic pitfall.  Int J Clin & Exp Pathol. 2014;7:378-385.

11. Xu X, Su M, Levy NB, Mohtashamian A, Monaghan S, Kaur P, Zaremba C, Garcia R, Broome HE, Dell'aquila ML, Wang HY*. Myeloid neoplasm with t(3;8)(q26;q24): report of six cases and review of the literature. Leuk Lymphoma. 2014;55:2532-2537.

12. Perry AM, Warnke RA, Hu, Q, Gaulard P, Copie-Bergman C, Alkan S, Wang HY, Cheng JX, Bacon CM, Ranheim E, Kucuk C, Hu XZ, Weisenburger DD, Jaffe ES, Chan WC. Indolent T-cell lymphoproliferative disease of the gastrointestinal tract. Blood. 2013;122:3599-3606. PMID: 24009234.

13. Garmy-Susini B, Avraamides CJ, Desgrosellier JS, Schmid MC, Foubert P, Ellies LG, Lowy AM, Blair SL, Vandenberg SR, Datnow B, Wang HY, Cheresh DA, Varner J. PI3Kα activates integrin α4β1 to establish a metastatic niche in lymph nodes. Proc Natl Acad Sci U. S. A. 2013;110:9042-9047. PMID: 23671068.

14. Wang HY* and Shabaik AS. Metastatic Merkel cell carcinoma involving the bone marrow with chronic lymphocytic leukemia mimicking Richter transformation. Blood. 2013;122:2776.

15. Jamshidi P, Chen JY, Wang HY, Chen CC. Anaplastic lymphoma kinase-positive large cell lymphoma of the anterior skull base: Report of an unusual case and review of the literature. Surg Neurol Int. 2013;4:57. doi: 10.4103/2152-7806.110656.

16. Visco C, Tzankov A, Xu-Monette ZY, Miranda RN, Tai YC, Li Y, Liu WM, d'Amore ES, Li Y, Montes-Moreno S, Dybkær K, Chiu A, Orazi A, Zu Y, Bhagat G, Wang HY, Dunphy CH, His ED, Zhao XF, Choi WW, Zhao X, van Krieken JH, Huang Q, Ai W, O'Neill S, Ponzoni M, Ferreri AJ, Kahl BS, Winter JN, Go RS, Dirnhofer S, Piris MA, Møller MB, Wu L, Medeiros LJ, Young KH.  Patients with diffuse large B-cell lymphoma of germinal center origin with BCL2 translocation have poor outcome, irrespective of MYC status: A report from an International DLBCL rituximab-CHOP Consortium Program Study. Hematologica. 2013;98:255-263.

17. Kato H, Liao Z, Mitsios JV, Wang HY, Deryugina EI, Varner JA, Quigley JP, Shattil SJ. The primacy of β1 integrin activation in the metastatic cascade. PLoS One. 2012;7(10).e46576. doi 10.1371/journal.pone.0046576. Epub 2012 Oct 3.

18. Li K, Ku G, Yan M, Broome HE, Kelner ML, and Wang HY*. A rare and unique case of aggressive IgE-lambda plasma cell myeloma in a 28-year-old woman presented initially as an orbital mass. Hum Pathol. 2012;43:2376-2384.

19. Xu X, Wang HY, Rashidi HH, Wong AK. Two cases of mantle cell lymphoma mimicking marginal zone lymphoma.  J Hematopathol. (online Pub DOI10.1007/s12308-012-0147-7).

20. Zheng J, Umikawa M, Cui C, Li J, Chen X, Zhang C, Hyunh HD, Kang X, Silvany R, Wan X, Ye J, Canto AP, Chen SH, Wang HY, Ward ES, Zhang CC. Immune inhibitory receptors bind ANGPTLs and support blood stem cells and leukemia development. Nature. 2012;485:656-662.

21. Rashidi HH, Xu X, Wang HY, Shafi NQ, Rameshkumar K, Messer K, Smith BR, and Rose MG.  Untility of peripheral blood flow cytometry in differentiating low grade versus high grade myelodysplastic syndrome (MDS) and in the evaluation of cytopenias. Int J Clin Exp Pathol. 2012;5:210-215.

22. Pan ZG, Zhang QY, Lu J, Quinto T, Rozenvaald IB, Liu LT, Wilson D, Reddy V, Huang Q, Wang HY*, and Ren YS. Extracavity KSHV-associated large B-cell lymphoma: A distinct entity or a subtype of primary effusion lymphoma? Study of 9 cases and review of additional 43 cases.  Am J Surg Pathol. 2012;36:1129-1140.

23. Papanicollau-Sengos A, Wang-Rodriguez J, Wang HY, Lee RR, Wong A, Hansen LA, Mahooti, S, Rashidi HH. Rare case of a primary non-dural central nervous system low grade B-cell lymphoma and literature review. Int J Clin Exp Pathol. 2012;5:89-95.

24. Broome HE, Rassenti LZ, Wang HY, Meyer L, Kipps TJ. ROR1 is expressed on hematogones (non-neoplastic human B-lymphocyte precursors) and a minority of precursor-B acute lymphoblastic leukemia. Leuk Research 2011;35:1390-1394 (Epub doi:10.1016/ j.leukres.2011.06.021).

25. Visco C, Li Y, Green TM, Xu-Monette ZY, Miranda RN, Li Y, Tzankov A, Wen W, Liu WM, Kahl BS, Emanuele SG d'Amore, Montes-Moreno S, Dybkaer K, Chiu A, Tam W, Orazi A, Zu Y, Bhagat G, Winter JN, Wang HY, O'Neill S, Dunphy CH, His ED, Zhao XF, Go RS, Choi WWL, Zhou F, Czader M, Tong J, Zhao X, Johan HJM Han van Krieken, Huang Q, Ai WZ, Entzell J, Ponzoni M, Ferreri AJM, Piris MA, Moller MB, Bueso-Ramos CE, Medeiros LJ, Wu L, and Young KH. Comprehensive gene expression profiling and immunohistochemical studies support immunophenotypic algorithm for molecular subtype classification in diffuse large B-cell lymphoma. A report from the International DLBCL Rituximab-CHOP Consortium Program Study. Luekemia 2012;26:2102-2113.

26. Wang HY*, Thorson JA, Broome HE, Curtin PT, Dell’Aquila ML.  A t(4;22)(q12;q11.2) involving presumptive PDGFRA and BCR in a patient with mixed phenotype acute leukemia. Hum Pathol. 2011;42:2029-2036.

27. Seegmiller AC, Wang HY, Hladik C, Chen W. Uniform Expression of Notch1, Suppressor of B-cell Specific Gene Expression, in PlasmablasticLymphoma. Arch Pathol Lab Med. 2011;135:770-775.

28. Li K, Topps AMP, Wang HY*.  Anaplastic lymphoma kinase-positive diffuse large B-cell lymphoma presenting as an isolated nasopharyngeal mass: A case report and review of literature. Int J Clin Exp Pathol. 2011;23:190-196.

29. Wang HY*, Huang LJ, Liu Z, Garcia R, Li S, and Galliani CA. Erythroblastic sarcoma presents as bilateral ovarian masses in an infant with pure erythroid leukemia. Hum Pathol 2011;42:749-758.

30. Visco C, Malik JT, Xu Z, Hoeller S, Wiggins ML, Sanger WG, Chang J, Ranheim EA, Swerdlow SS, Gradowski JF, Serrrano S, Gascoyne R, Chan JC, Liu J, Liu Z, Campo E, Wang HY, Liu T, Dave S, Olsen B, Tzankov A, and Young KH.  Molecular characterization of mantle cell lymphoma presenting with clonal plasma cell component.  Am J Surg Pathol. 2011;35:177-189.

31. Xu X, Broome EH, Hooman HH, South ST, Dell’Aquila ML, Wang HY*. CD20dim-positive T-cell large granular lymphocytic leukemia in a patient with concurrent hairy cell leukemia and plasma cell myeloma. Int J Clin Exp Pathol. 2010;3:798-807.

32. Xiao W, Ando T, Kawakami Y, Wang HY, Kawakami T. Loss of SHP-1 tyrosine phosphorylation induces a Stat5-depedent, chronic myelomonocytic leukemia-like disease in Lyn/PLC-b3 double deficient mice. Blood. 2010;23:6003-3013.

33. Wang HY*, Li S, Woodford RL, Mills SE and Cousar JC. BCL2 Chromosomal Translocation Is Not a General Feature of the Interdigitating Dendritic Cell Sarcoma.  Diagn Mol Pathol. 2010; 19: 169-171.

34. Du S, Rashidi HH, Le DT, Kipps TJ, Broome HE, and Wang HY*. Systemic mastocytosis in association with chronic lymphocytic leukemia and plasma cell myeloma. Int J Clin Exp Pathol. 2010;3:448-457.

35. Wang HY*, Chen W, Fuda FS, and Karandikar NJ. Notch1 in primary effusion lymphoma: a clinicopathologic study. Modern Pathol. 2010;23:773-780.

This paper was a featured article for the June issue of Modern Pathology. In addition, the Cover of the June issue was from this paper.

36. Wang MX, Wang HY, Zhao XZ, Srilatha N, Ning J, Duff D, Taylor KH, Gruner BA, Shi H and Caldwell CW. A sensitive Molecular Method for Detection of Disseminating Hematopoietic Tumor Cells by Using Specific Epigenetic DNA Methylation Biomarkers. Int J Clin Exp Pathol. 2010;3:265-279.

37. Wang HY* and Tirado C. t(8;21)(q22;q22) translocation involving AML1 and ETO in B lymphoblastic leukemia. Human Pathol. 2010;41:286-292.

38. Deisch J, Fuda FF, Chen W, Karandikar N, Arbini AA, Zhou X and Wang HY. Segmental tandem triplication of mixed lineage leukemia (MLL) gene in an intravascular large B-cell lymphoma with multisystem involvement – A comprehensive morphologic, immunophenotytpic, cytogenetic and molecular cytogenetic antemortem study. Arch Path Lab Med.  2009;133:1477-1482.

39. Efune G, Sumer BD, Sarode VR, Wang HY and Myers LL. Interdigitating dendritic cell sarcoma of the parotid gland: Case report and literature review. Am J Otolaryngology-Head and Neck Surg. 2009;30:264-268.

40. Peng Y, Wang HY *and Molberg K. Cutaneous Colocalized Invasive Poorly Differentiated Carcinoma and Chronic Lymphocytic Leukemia /Small Lymphocytic Lymphoma of the Head and Neck: a Case Report and Review of the Literature.  Arch of Otolarygology - Head & Neck Surg. 2009;135:606-610.

41. Alatoom A, Elsabrouty R, Willis J, Boils C, Sarode R, Hashim I, and Wang HY. Fetal cerebral hemaorrhage in a patient with CD19-positive IgM-producing aggressive plasma cell myeloma, hyperviscositysyndrome and cryoglobulinemia.  Int J Clin Exp Pathol. 2009;2:498-507.

42. Wang HY*, Ding J, Vasaf MA, and Wilson KS. A bcr3/short form PML-RARa transcript is an acute promyelocytic leukemia resulted from a derivative chromosome 17 due to submicroscopic insertion of the PML gene into the RARalpha locus. Am J Clin Pathol. 2009;131:64-71.

43. Olteanu H, Wang HY, Chen W, McKenna RW and Karandikar NJ. Immunophenotypic studies of monoclonal gammopathy of undetermined significance. BMC Clinical Pathology 2008,8:13. Doi:10.1186/1472-6890-8-13. Article URL: http://www.biomedcentral.com/1472-6890/8/13.

44. Wang HY*, Karandikar NJ, Payne DA, Maleki A, Schult BA, Collins R and McKenna RW. A 3-Way Collision Tumor of the Upper Respiratory Tract: A Composite of 2 Immunophenotypically Distinct Mantle Cell Lymphomas and a Plasmacytoma. Human Pathol. 2008;39:781-787.

45. Maftoun-Banankhah S, Maleki A, Karandikar NJ, Arbini AA, Fuda FS, Wang HY and Chen W.  Multiparameter Flow Cytometric Analysis Reveals Low Percentage of

Bone Marrow Hematogones in Myelodysplastic Syndromes. Am J Clin Pathol. 2008;129:300-308.

46. Wang HY*, Wilson KS, McKenna RW, Xu Y and Karandikar NJ.  An Extranodal Nasal Natural Killer / T-cell Lymphoma With Isochromsome 7q10 as the Sole Cytogenetic Aberration Was Initially Diagnosed via Bone Marrow Biopsy.  Arch Path Lab Med. 2007;131:1709-1714.

47. Zhang H, Wang HY, Bassel-Duby R, Maass DL, Li P, Johnston WE, Horton, JW and Tao W. Role of Interleukin-6 in Cardiac Inflammation and Dysfunction after Burn Complicated by Sepsis. Am J Physiol Heart Circ Physiol. 2007;292: H2408-2416.

48. Wang HY, Bossler AD, Schaffer A, Tomczak E, DiPatri DD, Nowell PC, Frank DS and Bagg A.  A novel t(3;8)(q27;q24.1) translocation simultaneously involving both the BCL6 and CMYC genes in a diffuse large B-cell lymphoma. Cancer Genet & Cytogenet. 2007;172:45-53.

49. Wang HY and Wick MR. A 75-year-old-man with a solitary left orbital mass. Arch Path Lab Med. 2005;129:e165-e166.

50. Wang HY and Mills SE. KIT and RCC are useful in distinguishing chromophobe

renal cell carcinoma from the granular variant of clear cell renal cell carcinom. Am J

Surg Path. 2005;29:640-646.

51. Xu X, Yang D, Ding JH, Wang W, Chu PH, Dalton ND, Wang HY, Bermingham JR Jr, Ye Z, Liu F, Rosenfeld MG, Manley JL, Ross J Jr, Chen J, Xiao RP, Cheng H, and Fu XD. ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell. 2005;120:59-72.

Accompanying Preview article for the above paper by Cooper TA. Alternative Splicing Regulation Impacts Heart Development. Cell. 2005;120: 1-2.

The above article is also featured as Cover picture for the January’s first issue of Cell.

52. Wang HY*. A 54-year-old-man with diffuse subcortical lesions of the central nervous system. Arch Path Lab Med. 2004;128:e70-e72.

53. Wang HY, Xu X, Ding JH, Bermingham JB, Jr. and Fu XD. SC35 plays a role in T-cell development and alternative splicing of CD45.  Molecular Cell. 2001;7:331-3427.

54. Yeakley JM, Tronchere H, Olesen J, Dyck JA, Wang HY and Fu XD.  Phosphorylation regulates in vivo interaction and molecular targeting of serine/arginine-rich pre-mRNA splicing factors.  J Cell Biol. 1999;145:447-455.

55. Wang HY, Arden KC, Bermingham JB, Jr., Viars CS, Lin W, Boyer AD and Fu XD. Localization of serine kinases, SRPK1(SFRSK1) and SRPK2(SFRSK2), specific for the

SR family of splicing factors in mouse and human chromosomes. Genomics. 1999;57:

310-315.

56. Wang HY, Lin W, Dyck JA, Yeakley JM, Songyang Z, Cantley LC, and Fu XD, "SKPK2: A differentially expressed SR protein-specific kinase involved in mediating the

interaction and localization of Pre-mRNA splicing factors in mammalian cells. J Cell Biol. 1998;140:737-750.

57. Permpikul C. Wang HY, Kriett J, Konopka RG, Moser KM and Spragg RG.

Reperfusion lung injury after unilateral pulmonary artery occlusion. Respirology. 2000; 5:133-140.

58. Marsh JJ, Konopka RG, Lang LM, Wang HY, Pederson C, Reilly CF and Moser KM. Suppression of thrombolysis in a canine model of pulmonary embolism. Circulation. 1994;90:3091-3097.

59. He P and Wang HY. (Clinical Pathologic Conference) Cough, dyspnea, muscle weakness and hoarse voice. Chinese J Pathology. 1992;21:315-318.

60. Wang HY, Che DY and Li WY. The preventive effect of Radix Salviae Miltiorrhizae on Monocrotaline-induced pulmonary hypertension in rats. J Tongji Medical University. 1992;12:139-145.

Reviews

61. Broome HE, and Wang HY. A case of conccomitant T-cell large granular lymphocytic leukemia and plasma cell myeloma. Clin Adv Hemat & Oncol. 2011;9:958-959.

62. Minoo P, and Wang HY. ALK-immunoreactive neoplasia. Int J Clin Exp Pathol. 2012; 5:397-410.

Abstracts (selected)

1. Wang HY and Che DY. The preventive effect of Radix Salviae Miltiorrhizae on monocrotaline-induced pulmonary hypertension. 1st International Chinese Congress on Thoracic Diseases. 12/11-13, China.

2. Hirata K, Nibhanupudy BN, Kim SS, Kapelanski DP, Jamieson SW, Bloor CM, Wang HY and Wolf P. Reduction of transplant arteriosclerosis with long term administration of 15-deoxyspergualin. 4th Annual Meeting and Scientific Sessions. 4/23-26, 1994. J Heart Lung Transplantation. 1994;S14:13.

3. Wang HY, Lin W and Fu XD. A new SR protein kinase family member that is highly expressed in brain and interacts with WW domain proteins. Eukaryotic mRNA Processing. 8/20-8/24, 1997. Cold Spring Harbor, New York.

4. Siebel CM, Feng L, Wang HY, FU XD and Gutherine C. SR protein phosphorylation in vivo: The SKY1 kinase affects NPL3 localization. Eukaryotic mRNA Processing. 8/20-8/24, 1997. Cold Spring Harbor, New York.

5. Saleem A, Li XG, Wang HY, Fu XD and Rubin E. Interaction between topoisomerase I and an SR protein kinase. 89th Annual Meeting of American Association for Cancer Research. 3/28-4/1, 1998. New Orleans, LA.

6. Wang HY and Fu XD. Targeted gene disruption in mice revealed a critical role of SC35 in T-cell development and maturation. 5th Annual Meeting of the RNA Society. 5/30-6/4, 2000. University of Wisconsin, Madison.

7. Wildemore BM, Carlin A, Wang H, Goldsmith K, Kwiatkowski JL, Biegel J, Wilmoth D, Choi JK and Edmonston TB. Single-stranded conformational polymorphism analysis improves radioactive detection of unequal X-inactivation – a case of childhood myelodysplastic syndrome. J Molecular Diagnostics. 2005;7:45.

8. Wang HY and Mills SE. KIT and RCC are useful in distinguisging chromophobe renal cell carcinoma from the granular variant of conventional renal cell carcinoma. Poster #72, 2005 Annual USCAP meeting, San Antonio, TX.

9. Olteanu H, Wang HY, Chen W, Mckenna RW and Karandikar NJ. Immunophneotypic identification of high-risk monoclonal gammopathy of undetermined significance. Lab Invest. 2007;87:255A.

10. Wang HY, Xu Y, McKenna RW, Karandikar NJ and Doolittle J.  Acute myeloid leukemias with a CD34(-)/HLA-DR(-) immunophenotype encompass a wide range of morphologic subtypes. Lab Invest. 2007;87:240A.

11. Karandikar NJ, Fuda F, Nussenzveig D, Maleki A, Wilson KS, Wang HY and MeKenna RW. Case #750160 for 2007 Workshop of Society for Hematopathology and European Association for Haematopathology. 02/2007.

12. Peters J, Karandikar NJ, Fuda F, Arbini AA, Wang HY and Chen W. Acute megakaryoblastic leukemia: immunophenotypic differences in patients with and without Down Syndrome. Modern Pathol. 2008;21(Suppl 1):269A

13. Kapur P, Rekheja D, Wang HY, Ashfag R, McKenna RW and Chen W. Nearly uniform expression of ID2 and Notch -1, Suppression of B-cell specific gene expression, in pediatric classical Hodgkin Lymphoma. Modern Pathol. 2008;21(Suppl 1):259A

14. Wang HY, Fuda FS and Karandikar NJ. Notch 1 in primary effusion lymphoma: clinicopathologic study. Lab Invest. 2009;89(Suppl 1):289A-290A.

15. Seegmiller AC, Maleki A, Kabbani P, Shang P, Wang HY and Chen W. Uniform expression of Notch1, suppression of B-cell specific gene expression, in plasmablastic lymphoma. Lab Invest. 2009;89 (Suppl 1). 285A.

16. Wang MX, Zhao XZ, Srilatha N, Wang HY, Ning J, Duff D, Taylor KH, Gruner BA, Shi H and Caldwell CW. A sensitive Molecular Method for Detection of Disseminating Hematopoietic Tumor Cells by Using Specific Epigenetic DNA Methylation Biomarkers.  Blood.  2008;112: Abstract 4850. (The 50th annual Am Society of Hematol meeting, December 2008, San Francisco, CA).

17. Young KH, Patten N, Eickhoff JC, Roque G, Malik JT, Yan L, Kanehira K, Twohig M, Waknitz M, Kahl BS, Go RS, Møller MB, Tzankov A, Moreno SM, Piris MA, Visco C, Dybkær K, Chiu A, Orazi A, Chang JC, Bhagat G, Owen O’Connor O, Winter J, Wang HY, Dunphy C,  O’Neill S, His E, Zhao F, Krinstin Hunt K, Chen W, Choi W, Zhou F, Czader M, Yong L, Selvaggi S, Malter JS, Wu L. Clinical impact of TP53 gene mutations in diffuse large B-cell lymphoma (DLBCL): An international DLBCL R-CHOP Consortium Program Study. Blood. 2009;114:967 (Platform presentation at 2009 Annual American Society of Hematology meeting).

18. Woodford RL, Wang HY, Li S, Mills SE and Cousar JB.  t(14;18)-Negative Interdigitating Dendritic Cell Sarcomas: A Morphologic and Immunohistochemical Review. Modern Pathol. 2010;23 (Supplement 1): 330A.

19. Malik JT,…Wang HY, … Young KH. Validation and application of new immunostain algorithm for molecular subtype classification of diffuse large B-cell lymphoma (DLBCL): An International DLBCL Rituxan-CHOP Consortium Program Study. Modern Path. 2010:23 (Supplement 1): 426A.

20. Malik JT, Wiggins ML, Sanger WG, Chang J, Ranheim EA, Steven Swerdlow S, Serrrano S, Gascoyne R, Chan JC, Campo E, Wang HY, Tzankov A, and  Young KH.  Clonal assessment of mantle cell lymphoma with plasmacytic differenation. Modern Path. 2010;23 (supplement 1): 389A.

21. Xu X, Broome HE, Hooman HH, Wang HY. CD20-positive T-Cell Large Granular Lmphocytic Leukemia with Concurrent Hairy Cell Leukemia and Plasma Cell Myeloma: a Case Report and Review of the Literature. Presented at the 2010 ASCP Annual Meeting.

22. Canepa M, Carrigg A, Synkowski DR, Wang HY, Lee R.  A case of plasma cell leukemia with skin manifestation. Presented at the Am Soc Dermat 47th Annual Meeting . Oct 7-10, 2010. Atlanta, GA.

23. Papnicolau-Sengos A, Rashidi H, Wang-Rodriguez J, Wang HY, Hansen LA, Lee RR, Nahooti S. An Unusual case of primary central nervous system low-grade B-cell lymphoma.  Presented at 2010 CAP Annual Meeting. Chicago, IL.

24. Wang HY, Thorson JA, Broome EH, Rashidi HH, Curtin PT, Dell’Aquila ML. t(4;22)(q12;q11.2) involving PDGFRA and BCR in a patient with mixed phenotype acute leukemia. Accepted for poster presentation at XVth European Association for Hematopathology Society. Uppasala, Sweden. 09/26/2010.

25. Broome EH, Wang HY, Meyer L, Go W, Rassenti L, Kipps TJ. ROR1 is expressed on the surface of non-neoplastic human B-lymphocyte precursors (hematogones) and on a subset of B acute lymphoblastic leukemia. Blood. (Poster presentation at the 2010 ASH Annual Meeting)

26. Pan Z, Lu Z, Liu L, Wilson D, Reddy V, Wang HY, Ren Y. Extracavitary KSHV+ large B-cell lymphoma: Time to have a new name? Modern Pathol. 2011;24(Suppl 1): 313A.

27. Su M, Rakheja D, Wang HY, Fuda F, Chen W. Diagnostic value of CD31 immunohistochemistry in evaluation of acute myeloid leukemia with megakaryocytic differentiation. Modern Pathol. 2011;24(Suppl 1): 323A.

28. Wang HY, Broome EH, Wildhopf GF, Dell’Aquila DL, Rassenti LZ, Kipps TJ. Immunophenotypic, cytogenetic and molecular characterization of biphenotypic B-chronic lymphocytic leukemia. Modern Pathol. 2011;24(Suppl 1): 328A

29. Xu X, Rashidi HH, Wang HY, Wong AK. Lack of SOX11 expression in marginal zone-like mantle cell lymphoma: Is it an indolent variant? Poster presented at the 2011 CAP Annual Meeting).

30. Visco C, Li Y, Green TM, Xu-Monette ZY, Miranda RN, Li Y, Tzankov A, Wen W, Liu WM, Kahl BS, Emanuele SG d'Amore, Montes-Moreno S, Dybkaer K, Chiu A, Tam W, Orazi A, Zu Y, Bhagat G, Winter JN, Wang HY, O'Neill S, Dunphy CH, His ED, Zhao XF, Go RS, Choi WWL, Zhou F, Czader M, Tong J, Zhao X, Johan HJM Han van Krieken, Huang Q, Ai WZ, Entzell J, Ponzoni M, Ferreri AJM, Piris MA, Moller MB, Bueso-Ramos CE, Medeiros LJ, Wu L, and Young KH.. The t(14;18)(q32;q21) Characterizes a Subset of Patients with Diffuse Large-B Cell Lymphoma of Germinal Center Origin with Poor Outcome: Report From the International DLBCL Rituximab-CHOP Consortium Program Study. Blood (Oral presentation at ASH 2011

31. Xu X, Su M, Levy NB, Kaur P, Garcia R, Mohtashamian A, Broome HE, Dell’Aquila ML, and Wang HY. Myeloid neoplasia with t(3;8)(q26;q24): report of four cases and review of literature. Modern Pathol. 2012;25 (suppl 2): 382A.USCAP 2012

32. Diaz-Perez JA, Amaro D, Dell’Aquila ML, and Wang HY. Comprehensive molecular cytogenetic analysis by fluorescence in situ hybridization in patients with chronic lymphocytic leukemia. Modern Pathol. 2012: 25 (suppl 2): 332A. USCAP 2012.

33. Browne SH, Diaz-Perez JA, Reid E, Li H, Messer K, Wang HY, VandenBerg S. mTOR pathway is activated in AIDS-related diffuse large B-cell lymphoma (DLBCL) and is associated with a germinal center immunophenotype with EBV co-infection. Arch Path Lab Med. 2012;136:1073. CAP 2012.

34. Perry A, Warnke R, Hu Q, Rosenwald A, Gaulard P, Copie-Bergman C, Geissinger E, Wang HY, Ranheim E, Weisenburger DW, Jaffe ES, Chan W. Indolent T-cell lymphoproliferative disease of the gastrointestinal tract: report of seven cases. XVI European Association for Haematopathology (Platform Presentation). 2012.  Lisboa, Portuguese.

35. Minoo P, Fu XD, Wang HY. SRPK1 and SRPK2: potential diagnostic marker for diffuse large B-cell lymphoma. Mod Pathol. 2013;26(suppl 2):348A. USCAP 2013.

36. Yin L, Xu J, Li M, Reddy V, Zhou Q, Liu H, Chu P, Zhang P, Huang Q, Gao Z, Wang HY, Liang X, Pan Z. Bob1 and Oct2 expression in lineage determination of B-cell lymphomas negative for conventional B-cell markers. Mod Pathol. 2013;26(suppl 2):369A. USCAP 2013.

37. Minoo P, Liu S, Choi M, Wang HY. Metastatic Merkel cell carcinoma in the bone marrow of a patient with chronic lymphocytic leukemia. Arch Path Lab Med. 2013;137:1344 (presented at the 2013 Annual CAP meeting) (Erratum Volume 137; issue 12).

38. Nguyen JC, Wang HY. De novo CD5-positive large B-cell lymphoma: immunophenotypic, cytogenetic, and clinical Study of 16 cases.  Mod Pathol. 2014;27(suppl 2):364A. USCAP 2014.

39. Nguyen JC, Yang Q, Broome HE, Wang HY. Metastatic carcinoma and sarcoma in bone marrow: 12-year experience from a single institution. Mod Pathol. 2014;27(suppl 2):365A. USCAP 2014.

40. Yang Q, Wang HY. A case of fatal cutaneous gamma-delta T cell lymphoma: delayed diagnosis and the misleading effect of negative ancillary tests. ASCP Oct 8-10, 2014. Tampa, FL.

Papers selected for the Cover of Journal

1. Cover of Cell for the January 2005 issue from Xu X, Yang D, Ding JH, Wang W, Chu PH, Dalton ND, Wang HY, Bermingham JR Jr, Ye Z, Liu F, Rosenfeld MG, Manley JL, Ross J Jr, Chen J, Xiao RP, Cheng H, and Fu XD. ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell. 2005;120:59-72.

2. Cover of Modern Pathology for the June 2010 issue from Wang HY, Fuda FS, Chen W, and Karandikar NJ. Notch1 in primary effusion lymphoma. Modern Pathol. 2010;23:6773-780.

Book Chapter

1. Wang HY. 第十五章 淋巴造血系统肿瘤。464-471页。 乳腺诊断病理学案例精选。丁华野 （总主编）， 刘彤华（主审），张祥盛， 步宏（主编）。 人民卫生出版社。北京， 中国，

2. Wang HY, Wong-Seftan I, Reid EG. Plasmablastic lymphoma. In The Encyclopedia of AIDS. Richman D et al (Eds). 2014

3. Kipps TJ and Wang HY. Classification of malignant lymphoid disorders (Chapter 92). Williams Hematology 8th Edition, Kaushansky et al Eds. McGraw-Hill, New York. 2010.

4. Thorson JA, Wang HY. Jak2 mutations in myeloproliferative neoplasms. In: Diagnostic Molecular Pathology in Practice. Schrijver I, Editor. Springer-Verlag Berlin and Heidelberg GMBH & Co. K, Berlin.

5. Thorson JA, Wang HY. Genetic analysis in a case of mixed phenotype acute leukemia. In: Diagnostic Molecular Pathology in Practice. Schrijver I, Editor. Springer-Verlag Berlin and Heidelberg GMBH & Co. K, Berlin.

6. HematologyOutlines - An Online Textbook & Atlas of Hematology at http://hematologyoutlines.com. Rashidi HH, Blaustein J, Nguyen JC and Wang HY, at al Ed.

Editorial Board for Scientific Journals

12/2007-Present Member of Senior Editorial International Journal of Clinical

Board & Experimental Pathology.

09/2011-Present Associate Editor Journal of Hematologic Malignancies

08/2013-Present Member of Advisory American Journal of Human

Board (AdEB) Pathology (http://ivyunion.org/index.

Php/pathology/about/editorialTeam).

Ad Hoc Reviewer for Professional Journals

1.  Human Pathology

2.  Archives of Pathology and Laboratory Medicine

3.  Leukemia & Lymphoma

4.  Cancer management and Research

5.  Journal of hematologic Malignancy

6.  American Journal of Reproductive Immunology

7.  Journal of Head and Neck Pathology

8.  Cancer

9.  Blood

10. Reproductive Immunology

11. Experimental Hematology

Reviewer for Book Chapter (10/2009)

Gascoyne RD and Skinnider BF. Chapter 98. Pathology of Malignant Lymphomas. Williams Hematology 8th Edition, Kaushansky et al Eds.

Aknowledged by the following publications:

1.Schenk PW, Boersma AWM, Brandsma JA, den Dulk H, Burger H, Stoter G, Brouwer J, Nooter K. SKY1 is involved in Cisplatin-induced cell kill in Saccharomyces cerevisiae, and inactivation of its human homologue, SRPK1, induces Cispaltin resistance in a human ovarian carcinoma cell line.  Cancer Res. 2001; 61:6982-6986.

2. Li HY, Grubb M, Panda M, Jones R. A sore throat-potentially life-threatening? J Gen Intern Med. 2009;24:872-875.

Significant/Representative Publications:

1. Wang HY, McMahon C, Ali S, Young L, Yekezare S, Ross J, and Ball E. Novel FNDC3B and EVI1 fusion and WT1 L378fs* 7 frameshift mutation in an acute myeloid leukemia with cytomorphologic and immunophenotypic features reminiscent of acute promyelocytic leukemia.  Br J Haematol. 2015. doi. 10.1111/bjh.13552. PMID: 26147192.  Impact factor: 4.711.

2. Xu X, Su M, Levy NB, Mohtashamian A, Monaghan S, Kaur P, Zaremba C, Garcia R, Broome HE, Dell'aquila ML, Wang HY. Myeloid neoplasm with t(3;8)(q26;q24): report of six cases and review of the literature. Leuk Lymphoma. 2014;55:2532-2537.Impact factor: 2.891

3. Peery AM, Warnke RA, Hu Q, Gaulard P, Copie-Bergman C, Alkan S, Wang HY, Cheng JX, Bacon CM, Ranheim E, Kucuk C, Hu XZ, Weisenburger DD, Jaffe ES, Chan WC. Indolent T-cell lymphoproliferative disease of the gastrointestinal tract. Blood. 2013;122:3599-3606. PMID: 24009234.  Impact factor: 10.452

4. Zheng J, Umikawa M, Cui C, Li J, Chen X, Zhang C, Hyunh HD, Kang X, Silvany R, Wan X, Ye J, Canto AP, Chen SH, Wang HY, Ward ES, Zhang CC. Immune inhibitory receptors bind ANGPTLs and support blood stem cells and leukemia development. Nature. 2012;485:656-662.  Impact factor: 41.456

5. Pan ZG, Zhang QY, Lu J, Quinto T, Rozenvaald IB, Liu LT, Wilson D, Reddy V, Huang Q, Wang HY, and Ren YS. Extracavity KSHV-associated large B-cell lymphoma: A distinct entity or a subtype of primary effusion lymphoma? Study of 9 cases and review of additional 43 cases.  Am J Surg Pathol. 2012;36:1129-1140. Impact factor: 4.591

6. Wang HY, Huang LJ, Liu Z, Garcia R, Li S, and Galliani CA. Erythroblastic sarcoma presents as bilateral ovarian masses in an infant with pure erythroid leukemia. Hum Pathol 2011;42:749-758.  Impact factor: 2.769

7. Wang HY, Chen W, Fuda FS, and Karandikar NJ. Notch1 in primary effusion lymphoma: a clinicopathologic study. Modern Pathol. 2010;23:773-780. Impact factor: 4.176.

This paper was on the cover of this particular issue.

8. Wang HY, Ding J, Vasaf MA, and Wilson KS. A bcr3/short form PML-RARa transcript is an acute promyelocytic leukemia resulted from a derivative chromosome 17 due to submicroscopic insertion of the PML gene into the RARalpha locus. Am J Clin Pathol. 2009;131:64-71.  Impact factor: 2.473

9. Xu X, Yang D, Ding JH, Wang W, Chu PH, Dalton ND, Wang HY, Bermingham JR Jr, Ye Z, Liu F, Rosenfeld MG, Manley JL, Ross J Jr, Chen J, Xiao RP, Cheng H, and Fu XD. ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell. 2005;120:59-72.  Impact factor: 32.242

Accompanying Preview article for the above paper by Cooper TA. Alternative Splicing Regulation Impacts Heart Development. Cell. 2005;120: 1-2.

The above article is also featured as Cover picture for the January’s first issue of Cell.

10. Wang HY, Xu X, Ding JH, Bermingham JB, Jr. and Fu XD. SC35 plays a role in T-cell development and alternative splicing of CD45.  Molecular Cell. 2001;7:331-3427. Impact factor: 14.108

11. Wang HY, Lin W, Dyck JA, Yeakley JM, Songyang Z, Cantley LC, and Fu XD, "SKPK2: A differentially expressed SR protein-specific kinase involved in mediating the

interaction and localization of Pre-mRNA splicing factors in mammalian cells. J Cell Biol. 1998;140:737-750. Impact factor: 9.834.