叶菁,中国人民解放军第四军医大学,第一附属医院病理科/基础部病理学教研室副主任,教授,博士生导师,主要从事中枢神经系统肿瘤的临床诊断和分子机制研究。现担任全军病理学专业委员会委员、中华医学会病理学分会分子病理学组(筹)委员、中国医师协会病理医师分会分子病理委员会委员和中国抗癌协会肿瘤标志委员会青年委员。曾先后在香港科技大学、清华大学、加拿大安大略癌症研究所(OCI)进行了多年的博士后研究工作,现主要进行脂肪肝与胶质瘤发生过程中的代谢学机制研究。作为课题负责人,承担和完成了“重大新药创制”科技重大专项1项,国家自然科学基金5项,并参与多项国家863项目、国家自然科学基金重点项目、全军“十五”重点项目的研究工作。近年来,以第一作者和通讯作者在 Cell Metabolism、Hepatology、Diabetes 等杂志上发表多篇研究论文。2015年获得中国杰出青年病理医师奖(中国医师协会)。
代表性著作:
[1] Wang C, Zhao YL, Gao X, Li L, Yuan Y, Liu F, Zhao LJ, Wu J, Hu PZ, Zhang XM, Gu Y, Xu YQ, Li ZS, Zhang HZ, Ye J*. Perilipin 5 improves hepatic lipotoxicity by inhibiting lipolysis. Hepatology. 2015 Mar;61(3):870-82 (通讯作者,IF: 11.19)
[2] Zhang LJ, Wang C, Yuan Y, Wang H, Wu J, Liu F, Li L, Gao X, Zhao YL, Hu PZ, Li P*, Ye J*. Cideb facilitates the lipidation of chylomicrons in the small intestine. J Lipid Res. 2014; 55(7):1279-87. (通讯作者,IF: 4.386)
[3] Feng XY, Yuan Y, Wang C, Feng J, Yuan ZY, Zhang XM, Sui W, Hu PZ, Zheng PF, Ye J*. Autophagy involved in lipopolysaccharide-induced foam cell formation is mediated by adipose differentiation-related protein. Lipids Health Dis. 2014;13:10. (通讯作者,IF: 2.015)
[4] Yu M, Wang H, Zhao J, Yuan Y, Wang C, Li J, Zhang LJ, Zhang LY, Li Q*, Ye J*. Expression of CIDE proteins in clear cell renal cell carcinoma and their prognostic significance. Mol Cell Biochem. 2013;378(1-2):145-51. (通讯作者,IF: 2.329)
[5] Yuan Y, Li P*, Ye J*. Lipid homeostasis and the formation of macrophage-derived foam cells in atherosclerosis. Protein Cell. 2012, 3(3): 173–181. (通讯作者,IF: 3.22)
[6] Li H, Song Y, Zhang LJ, Gu Y, Li FF, Pan SY, Jiang LN, Liu F, Ye J*, Li Q*. LSDP5 enhances triglyceride storage in hepatocytes by influencing lipolysis and fatty acid β-oxidation of lipid droplets. PLoS One. 2012;7(6):e36712. (共同通讯作者,IF: 4.092)
[7] Li H, Song Y, Zhang LJ, Li FF, Gu Y, Zhang J, Dong WP, Xue L, Zhang LY, Liu F, Wang J, Jiang LN, Ye J*, Li Q*. Cell death-inducing DFF45-like effector b (Cideb) is present in pancreatic beta-cells and involved in palmitate induced beta-cell apoptosis. Diabetes Metab Res Rev. 2012;28(2):145-55. (共同通讯作者,IF: 3.373)
[8] Cao X, Gu Y, Jiang L, Wang Y, Liu F, Xu Y, Deng J, Nan Y, Zhang L, Ye J*, Li Q*. A new approach to screening cancer stem cells from the U251 human glioma cell line based on cell growth state. Oncol Rep. 2013;29(3):1013-8. (共同通讯作者,IF: 2.297)
[9] Ye J#, Li JZ, Liu Y, Li X, Yang T, Ma X, Li Q, Yao Z, Li P. Cideb, an ER- and lipid droplet-associated protein, mediates VLDL lipidation and maturation by interacting with apolipoprotein B. Cell Metabolism. 2009;9(2):177-90. (第一作者,IF = 16.107)
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