于文东

山东人德州地区乐陵市人,祖籍文登,

1992-1997 潍坊医学院  临床医学

1997-2000 首都儿科研究所  病毒学硕士

2000-2006 年   美国贝勒医学院就读病毒学 博士

2006-2010美国贝勒医学院病理系 博士后

2010-2014在迈阿密大学(University of Miami/Jackson Memorial Hospital)病理住院医生

2014-2015 安德森癌症中心做细胞病理临床fellow专业培训

2015至今 贝勒医学院做助理教授。

合作发表过10几篇文章,参加过两本书籍撰写。获得美国国防部的研究基金1项。擅长细胞病理,头颈和软组织病理诊断,热爱教学,临床工作,并尽力协调科研工作。希望和广大病理工作人和爱好者交流学习。


CURRENT POSITION

Assistant Professor, 01/2016–Present,

Baylor College of Medicine


EDUCATION

M.D., 09/1992–07/1997, Weifang Medical College, China

Ph.D., Molecular Virology, 10/2000–10/2006, Baylor College of Medicine

M.S., Molecular Virology, 09/1997–07/2000,

Capital Institute of Pediatrics, China


PROFESSIONAL EXPERIENCE

Instructor Pathologist, 08/2015–12/2015,

Baylor College of Medicine

Cytopathology Fellow, 07/2014–06/2015

MD Anderson Cancer Center, Houston, Texas

Resident, Anatomic and Clinical Pathology, 07/2010–06/2014,

University of Miami/Jackson Memorial Hospital

Chief Resident, Anatomic and Clinical Pathology, 07/2012–06/2013, University of

Miami/Jackson Memorial Hospital

Research Postdoctoral Associate, 10/2006–06/2010,

Baylor College of Medicine


AWARDS

Faculty teaching award, 2015-2016, Department of Pathology, Baylor College of

Medicine

Prostate Postdoctoral Training Fellowship, 2009–2010,

$113,196.00, from Department Of Defense


JOURNAL ARTICLES

1. Zhang J, Feider CL, Nagi C, Yu W, Carter SA, Suliburk J, Cao HS, Eberlin LS.

Detection of Metastatic Breast and Thyroid Cancer in Lymph Nodes by

Desorption Electrospray Ionization Mass Spectrometry Imaging. J Am Soc Mass

Spectrom. 2017 Feb 28. doi: 10.1007/s13361-016-1570-2. [Epub ahead of print]

PMID: 28247296

2. Zhang J, Yu W, Ryu S, Lin J, Buentello G, Tibshirani R, Suliburk J, Eberlin L.

Cardiolipins are biomarkers of mitochondria-rich thyroid oncocytic tumors.

Cancer Res. 2016 Sep 22. pii: canres.1545.2016. [Epub ahead of print] PubMed

PMID: 27659048.

3. Zhang J, Yu W, Suliburk J, Eberlin LS. Will Ambient Ionization Mass

Spectrometry Become an Integral Technology in the Operating Room of the

Future? Clin Chem. 2016 Sep;62(9):1172-4. doi: 10.1373/clinchem.2016.258723.

PubMed PMID: 27430706.

4. Villada G, Farooq U, Yu W, Diaz JP, Milikowski C. Extramammary Paget disease

of the vulva with underlying mammary-like lobular carcinoma: a case report and

review of the literature. Am J Dermatopathol. 2015 Apr;37(4):295-8. Review.

PubMed PMID: 24752217.

5. Feng S, Shao L, Yu W, Gavine P, Ittmann M. Targeting fibroblast growth factor

receptor signaling inhibits prostate cancer progression. Clin Cancer Res. 2012 Jul

15;18(14):3880-8. doi: 10.1158/1078-0432.CCR-11-3214. PubMed PMID:

22573348; PubMed Central PMCID: PMC4654778.

6. Ramakrishnan R, Yu W, Rice AP. Limited redundancy in genes regulated by

Cyclin T2 and Cyclin T1. BMC Res Notes. 2011 Jul 26;4:260. doi:

10.1186/1756-0500-4-260. PubMed PMID: 21791050; PubMed Central PMCID:

PMC3160394.

7. Yu W, Feng S, Dakhova O, Creighton CJ, Cai Y, Wang J, Li R, Frolov A, Ayala G,

Ittmann M. FGFR-4 Arg388 enhances prostate cancer progression via

extracellular signal-related kinase and serum response factor signaling. Clin

Cancer Res. 2011 Jul 1;17(13):4355-66. doi: 10.1158/1078-0432.CCR-10-2858.

PubMed PMID: 21622724; PubMed Central PMCID: PMC3131485.

8. Miao Z, Gao Y, Bindels RJ, Yu W, Lang Y, Chen N, Ren H, Sun F, Li Y, Wang X,

Shao L. Coexistence of normotensive primary aldosteronism in two patients

with Gitelman's syndrome and novel thiazide-sensitive Na-Cl cotransporter

mutations. Eur J Endocrinol. 2009 Aug;161(2):275-83. doi:

10.1530/EJE-09-0271. PubMed PMID: 19451210.

9. Wang J, Cai Y, Yu W, Ren C, Spencer DM, Ittmann M. Pleiotropic biological

activities of alternatively spliced TMPRSS2/ERG fusion gene transcripts.

Cancer Res. 2008 Oct 15;68(20):8516-24. doi: 10.1158/0008-5472.CAN-08-1147.

PubMed PMID: 18922926; PubMed Central PMCID: PMC2597580.

10. Yu W, Ramakrishnan R, Wang Y, Chiang K, Sung TL, Rice AP. Cyclin

T1-dependent genes in activated CD4 T and macrophage cell lines appear

enriched in HIV-1 co-factors. PLoS One. 2008 Sep 5;3(9):e3146. doi:

10.1371/journal.pone.0003146. PubMed PMID: 18773076; PubMed Central

PMCID: PMC2519787.

11. Wang J, Yu W, Cai Y, Ren C, Ittmann MM. Altered fibroblast growth factor

receptor 4 stability promotes prostate cancer progression. Neoplasia. 2008

Aug;10(8):847-56. PubMed PMID: 18670643; PubMed Central PMCID:

PMC2481572.

12. Yu W, Wang Y, Shaw CA, Qin XF, Rice AP. Induction of the HIV-1 Tat

co-factor cyclin T1 during monocyte differentiation is required for the

regulated expression of a large portion of cellular mRNAs. Retrovirology. 2006

Jun 9;3:32. PubMed PMID: 16764723; PubMed Central PMCID:

PMC1557533.

13. Haaland RE, Yu W, Rice AP. Identification of LKLF-regulated genes in

quiescent CD4+ T lymphocytes. Mol Immunol. 2005 Mar;42(5):627-41.

PubMed PMID:15607822.

14. Liu H, Yu W, Liou LY, Rice AP. Isolation and characterization of the human

DC-SIGN and DC-SIGNR promoters. Gene. 2003 Aug 14;313:149-59. PubMed

PMID: 12957386.

15. Yu W, You Zhang, Dongmei Chen and Yuan Qian. Sequence analysis of the

NSP4 gene of human rotavirus strains isolated in China. Bulletin of Medical

Research, 2004 Aug; 33(8): 12-16.


ABSTRACTS AND PROJECTS

1. Wendong Yu, Mouhammed A. Habra, Jane H. Zhou, Raghu Vikram, Ruth L. Katz.

Utility of immunohistochemical expression of Ki-67, Beta-Catenin, P53 and AR in

Assessment of Primary Adrenal Cortical Neoplasms (ACN). Oral Presentation at

USCAP 2015 Annual meeting, March 21 to 27, 2015

2. Wendong Yu, Claudia P. Rojas, MerceJorda, Monica T. Garcia-Buitrago,

ParvinGanjei-Azar, Carmen R. Gomez-Fernandez. DOG1 for the Diagnosis of Acinic

Cell Carcinoma in Cytology. Journal of the American Society of Cytopathology, Volume

2, Issue 1, Supplement , Page S51, October 2013, Poster presentation at the American

Society of Cytopathology 61st Annual Scientific Meeting 2013

3. Wendong Yu,Yeunjung Grant Kim, Carmen R. Gomez-Fernandez. A Rare Case of

Composite Tumor of Larynx with Aggressive Progression. Abstracts and Case Studies

From the College of American Pathologists 2013 Annual Meeting (CAP ‘13). Archives

of Pathology & Laboratory Medicine: October 2013, Vol. 137, No. 10, pp.

1343-1526.Poster presentation at CAP, the pathologists' meeting 2013

4. Wendong Yu and Carol Petito.An Unusual Case of Pineal-Region Schwannoma.

Abstracts and Case Studies From the College of American Pathologists 2013 Annual

Meeting (CAP ‘13). Archives of Pathology & Laboratory Medicine: October 2013, Vol.

137, No. 10, pp. 1343-1526.Poster presentation at CAP, the pathologists' meeting 2013

5. Julio Poveda, Wendong Yu, Carmen Gomez-Fernandez. Validation Study of

Telepathology on Neuropathology Frozen Section Diagnosis in a Multi-Hospital

Pathology Department. Modern Pathology: Volume 26, Issue S2 (Feb 2013), pp. 481A.

Poster Presentation at the USCAP 2013 Annual meeting, March 1-7, 2013.

6. Wendong Yu, Cesar Llanos, Pablo Bejarano, ParvinGanjei-Azar, Clara Milikowski.

Two Cases of Combined Goblet Cell Carcinoid and Serous Papillary Carcinoma.

Abstracts and Case Studies From the College of American Pathologists 2012 Annual

Meeting (CAP '12). Archives of Pathology & Laboratory Medicine: September 2012,

Vol. 136, No. 9, pp. 1005-1162.Poster Presentation at the CAP 2012 The Pathologists’

meeting, Sep 9-12, 2012

7. Wendong Yu, Cesar Llanos, VaniaNosé, Carmen Gomez-Fernandez. Validation

study of telepathology on frozen section diagnosis in a multi-hospital subspecialized

pathology department. Modern Pathology: Volume 25, Issue S2 (Feb 2012), pp.

509A.Platform Presentation at the USCAP 2012 Annual meeting, March 17-23, 2012

8. Wendong Yu, Saleem Umar, Saba Yasir, Mercy Jorda. CD44 full-thickness

immunoreactivity is more sensitive than CK5/6 for the diagnosis of flat urothelial

lesions with atypia. Modern Pathology: Volume 25, Issue S2 (February 2012), pp. 254A2.

Poster Presentation at the USCAP 2012 Annual meeting, March 17-23, 2012


BOOK CHAPTERS

1. Wendong Yu, SathiyamoorthySelvarajan, and Andrew E. Rosenberg.Vascular

Tumors of Bone, Chapter 13,Practical Orthopedic Pathology: A Diagnostic Approach,

Elsevier, In Press (2015 Spring)

2. Andrew P. Rice, Richard E. Haaland, Christine H. Herrmann, Li-Ying Liou,

Hongbing Liu, Tsu-Ling Sung, Yan Wang and Wendong Yu. Regulation of

expression of cyclin T1, the HIV-1 Tat co-factor, in monocytes and

macrophages.Chapter 7, HIV and the Macrophage, 2007: 79-88, published by

Research Signpost


LICENSURE AND BOARD CERTIFICATION

Diplomate of the American Board of Pathology, Anatomic and Clinical

Pathology, valid through 12/31/2024

Diplomate of the American Board of Pathology, Cytopathology, valid through

12/31/2025

State of Texas, Medical Physician and Surgeon, License: Q5131, valid through

08/31/2017

State of Pennsylvania, Medical Physician and Surgeon, License: MD450508,

expired


PROFESSIONAL SOCIETIES

United States and Canadian Academy of Pathology

College of American Pathologists

American Society of Cytopathology

Houston Society of Clinical Pathologists


TEACHING EXPERIENCE

I enjoyed teaching residents during daily signout. Additionally, I have lectured twice to

the ENT residents.

During residency, I voluntarily participated in many pathology laboratory sessions (>20)

with medical students on gross organ examination. Additionally, I was often assigned to

teach medical students during their pathology clerkship rotations (>10).

As a chief resident (PGY3) and later as a senior resident (PGY4), I worked very closely

with the first year residents during their first few months. Additionally, as a chief

resident, I was in charge of one year’s didactic curriculum and schedules


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