王曦，医学博士，纽约罗彻斯特大学病理与实验医学部助理教授。

教育经历

1978.03-1982.12  中山大学医学院  本科

1986.09-1989.08  中山大学医学院  硕士

研究生教育

1997.11-2001.06  西弗吉尼亚摩根敦，西弗吉尼亚大学医院病理科，住院医师

2001.07-2002.06  纽约，纪念Sloan Kettering肿瘤中心，肿瘤外科病理学

研究经历

1982.12-1986.08  中山大学医学院寄生虫系，讲师

1989.08-1991.09  广州医学院中心实验室，研究人员

1991.11-1996.09  马萨诸塞州波士顿，哈佛公共卫生学院，research fellow

1996.09-1997.11  马萨诸塞州波士顿，哈佛公共卫生学院，助理研究员

教育经历

1982.12-1986.08  中山大学医学院寄生虫系，讲师

2002.07至今  纽约，罗彻斯特大学病理系 助理教授

专业会员

美国临床病理学会（ASCP）

美国加拿大病理学会

研究兴趣

激素在乳腺癌发生过程中的作用，包括ER、 PR和AR，与其他癌基因和抑癌基因的相互作用。

出版物

1.  Sharlin Johnykutty, Ping Tang, Xi Wang, Dual expression of ER and TAP in normal/benign breast epithelium and TAP down regulation in ER positive breast cancer. Modern Pathology 2009, in press.

2.  Xi Wang, Jing Li, Sharlin Johnykutty, Shuyuan Yeh, Reduced Expression of Tocopherol-Associated Protein (TAP/Sec14L2) in human breast cancer. Cancer Investigation 2009, in press.

3.  Ming Chen, Xi Wang, Shuyuan Yeh, Sally Radovick, Generation and characterization of a complete null estrogen receptor mouse using Cre/LoxP technology. Molecular and Cellular Biochemistry 321(145-153), 2009.

4.  Rochelle Simon, Xi Wang, A46 XY Phenotypic female adolescent with bilateral gonadal tumors consisting of five different components. International Journal of Gynecological Pathology 27(407-411), 2008

5.  Ping Tang, Xi Wang, Linda Schiffhauer, Jianmin Wang, Patricia Bourne, Qi Yang, Andrew Quinn, and Steven Hajdu, Expression Patterns of ER-a, PR, Her2/neu and EGFR in different cell origin subtypes of high grade and non-high grade ductal carcinoma in situ. Annals of clinical & laboratory science 36(2), 2006

6.  Ping Tang, Xi Wang, Linda Schiffhauer, Steven Hajdu, Relationship between nuclear grade of ductal carcinoma in situ and cell origin markers. Annals of clinical & laboratory science 36(1), 2006

7.  Jakob Dupont, Xi Wang, Robert Soslow, Wilms tumor gene (WT1) and p53 expression in endometrial carcinomas: a study of 130 cases using tissue microarrays. Gynecologic Oncology 94(2), 2004.

8.  Xi Wang and Sharon L. Wenger, Multiple chromosome abnormalities following bone marrow transplant for chronic myelogenous leukemia. The Journal of the Association of Genetic Technologists 30 (1), 2004

9.  Xi Wang, David C. Christiani, Eugene J. Mark, Karl T. Kelsey, Carcinogen exposure, p53 alteration and K-ras mutation in synchronous multiple primary lung cancers. Cancer 1998

10.  Xi Wang, Kathleen M. Egan, Evangelos S. Gragoudas, Karl T. Kelsey, Constitutional alterations in p16 in patients with uveal melanoma. Melanoma Research Vol. 6 405-410, Dec. 1996

11.  Karl T. Kelsey, Heather Nelson, Xi Wang, Lung carcinogenesis: molecular and cellular mechanisms. Occupational Lung Disease. Thomson Science & Professional, 1997

12.  Xi Wang, David C. Christiani, John K. Wiencke, Eugene J. Mark, Karl T. Kelsey, Mutations in the p53 gene in lung cancer are associated with cigarette smoking and asbestos exposure. Cancer Epidemiology, Biomarkers &  Prevention. Vol. 4, 543-548, July/August 1995

13.  Fen Xia, Xi Wang, David W Yandell, Howard L. Liber. Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closely related human lymphoblast lines. Cancer research Vol 55, 12-15, January 1, 1995

14.  C. Mark Smith, Xi Wang, Howard Hu, and Karl T. Kelsey, A polymorphism in the -aminolevulinic acid dehydratase gene may modify the pharmacokinetics and toxicity of lead. Environmental Health Perspectives. Vol. 103, 248-253, Mar. 1995

演讲

1.  Joseph Weisensel and Xi Wang, Estrogen receptor (ER) and androgen receptor (AR) in normal human breast tissue and breast carcinoma. USCAP 2009, Boston, MA

2.  Sharlin Johnykutty and Xi Wang, Spindle cell (sarcomatous) carcinoma of the breast: Immunohistochemical profile and the clinical outcome. USCAP 2009, Boston, MA

3.  Sharlin Johnykutty, Xi Wang, Dual expression of alpha=Tocopherol Associated Protein (TAP) and ER in normal human breast epithelium and its down regulation in ER positive breast carcinomas. USCAP, Danver, CO, 2008

4.  Sharlin Johnykutty, Xi Wang, Reduced TAP expression in human breast cancer. USCAP, San Diego, CA, 2007

5.  Xi Wang, Jacob Dupunt, Robert Soslow, WT1 expression in ovarian and endometrial carcinomas using tissue microarrays. Annual meeting of United States and Canadian Academy of Pathology, 2003, Washington, DC

6.  Xi Wang, et al, P53 mutational analysis indicating that small cell and non-small cell carcinoma of the lung have a common histogenesis. Eighty-eighth Annual Meeting of American Association for Cancer Research (AACR), San Diego, CA, 1997

7.  Xi Wang, et al, p53 mutational status in lung cancer patients with multiple primary tumors. Eighty seventh Annual Meeting of AACR, Washington, DC, 1996

8.  Xi Wang, et al, Polymorphism in carcinogen activating genes are associated with the absence of mutations in the p53 gene in lung cancer. Eighty- seventh Annual Meeting of AACR, Washington, DC, 1996

9.  Xi Wang, et al, Mutations in the p53 gene in non-small cell lung cancer are associated with cigarette smoking and asbestos exposure. Eighty sixth Annual meeting of AACR, Toronto, Canada, 1995

10.  Xi Wang, et al, The mutational spectra of p53 in human lung cancer. Eighty-fifth Annual Meeting of AACR, San Francisco, CA, 1994